O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease

by Willayat Y. Wani, Xiaosen Ouyang, Gloria A. Benavides, Matthew Redmann, Stacey S. Cofield, John J. Shacka, John C. Chatham, Victor Darley-Usmar, Jianhua Zhang
Published 2017-07-01

The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinson's disease brain in association with the pathologic accumulation of alpha-synuclein

by Michael P. Nelson, Michel Boutin, Tonia E. Tse, Hailin Lu, Emily D. Haley, Xiaosen Ouyang, Jianhua Zhang, Christiane Auray-Blais, John J. Shacka
Published 2018-02-01

Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia

by Daniel Fil, Balu K. Chacko, Robbie Conley, Xiaosen Ouyang, Jianhua Zhang, Victor M. Darley-Usmar, Aamir R. Zuberi, Cathleen M. Lutz, Marek Napierala, Jill S. Napierala
Published 2020-07-01

Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

by Matthew Redmann, Gloria A. Benavides, Taylor F. Berryhill, Willayat Y. Wani, Xiaosen Ouyang, Michelle S. Johnson, Saranya Ravi, Stephen Barnes, Victor M. Darley-Usmar, Jianhua Zhang
Published 2017-04-01

Methods for assessing mitochondrial quality control mechanisms and cellular consequences in cell culture

by Matthew Redmann, Gloria A. Benavides, Willayat Yousuf Wani, Taylor F. Berryhill, Xiaosen Ouyang, Michelle S. Johnson, Saranya Ravi, Kasturi Mitra, Stephen Barnes, Victor M. Darley-Usmar, Jianhua Zhang
Published 2018-07-01

Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases

by Van N Huynh, Sheng Wang, Xiaosen Ouyang, Willayat Y Wani, Michelle S Johnson, Balu K Chacko, Anil G Jegga, Wei-Jun Qian, John C Chatham, Victor M Darley-Usmar, Jianhua Zhang, Jianhua Zhang
Published 2021-09-01

Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells

by Kenneth P. Hough, Jennifer L. Trevor, John G. Strenkowski, Yong Wang, Balu K. Chacko, Sultan Tousif, Diptiman Chanda, Chad Steele, Veena B. Antony, Terje Dokland, Xiaosen Ouyang, Jianhua Zhang, Steven R. Duncan, Victor J. Thannickal, Victor M. Darley-Usmar, Jessy S. Deshane
Published 2018-09-01