ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease.

by Leandra R Mangieri, Burton J Mader, Cailin E Thomas, Charles A Taylor, Austin M Luker, Tonia E Tse, Carrie Huisingh, John J Shacka
Published 2014-01-01

O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease

by Willayat Y. Wani, Xiaosen Ouyang, Gloria A. Benavides, Matthew Redmann, Stacey S. Cofield, John J. Shacka, John C. Chatham, Victor Darley-Usmar, Jianhua Zhang
Published 2017-07-01

The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinson's disease brain in association with the pathologic accumulation of alpha-synuclein

by Michael P. Nelson, Michel Boutin, Tonia E. Tse, Hailin Lu, Emily D. Haley, Xiaosen Ouyang, Jianhua Zhang, Christiane Auray-Blais, John J. Shacka
Published 2018-02-01