The impact of metallothionein-II on microglial response to tumor necrosis factor-alpha (TNFα) and downstream effects on neuronal regeneration

by Jacqueline Y. K. Leung, William R. Bennett, Anna E. King, Roger S. Chung
Published 2018-02-01

Tg2576 cortical neurons that express human Ab are susceptible to extracellular Aβ-induced, K+ efflux dependent neurodegeneration.

by Shannon Ray, Claire Howells, Emma D Eaton, Chris W Butler, Lana Shabala, Paul A Adlard, Adrian K West, William R Bennett, Gilles J Guillemin, Roger S Chung
Published 2011-04-01

The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons.

by Roger S Chung, Claire Howells, Emma D Eaton, Lana Shabala, Kairit Zovo, Peep Palumaa, Rannar Sillard, Adele Woodhouse, William R Bennett, Shannon Ray, James C Vickers, Adrian K West
Published 2010-01-01