Increased Density of Metallothionein I/II-Immunopositive Cortical Glial Cells in the Early Stages of Alzheimer's Disease

by Paul A. Adlard, Adrian K. West, James C. Vickers
Published 1998-11-01

α-Internexin immunoreactivity reflects variable neuronal vulnerability in Alzheimer's disease and supports the role of the β-amyloid plaques in inducing neuronal injury

by Tracey C. Dickson, Jyoti A. Chuckowree, Meng Inn Chuah, Adrian K. West, James C. Vickers
Published 2005-03-01

No difference in expression of apoptosis-related proteins and apoptotic morphology in control, pathologically aged and Alzheimer's disease cases

by Adele Woodhouse, Tracey C. Dickson, Adrian K. West, Catriona A. McLean, James C. Vickers
Published 2006-05-01

Metallothionein (MT) -I and MT-II expression are induced and cause zinc sequestration in the liver after brain injury.

by Michael W Pankhurst, David A Gell, Chris W Butler, Matthew T K Kirkcaldie, Adrian K West, Roger S Chung
Published 2012-01-01

Tg2576 cortical neurons that express human Ab are susceptible to extracellular Aβ-induced, K+ efflux dependent neurodegeneration.

by Shannon Ray, Claire Howells, Emma D Eaton, Chris W Butler, Lana Shabala, Paul A Adlard, Adrian K West, William R Bennett, Gilles J Guillemin, Roger S Chung
Published 2011-04-01

The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons.

by Roger S Chung, Claire Howells, Emma D Eaton, Lana Shabala, Kairit Zovo, Peep Palumaa, Rannar Sillard, Adele Woodhouse, William R Bennett, Shannon Ray, James C Vickers, Adrian K West
Published 2010-01-01