Prodrugs for Gene-Directed Enzyme-Prodrug Therapy (Suicide Gene Therapy)

by William A. Denny
Published 2003-01-01

The activity of SN33638, an inhibitor of AKR1C3, on testosterone and 17β-estradiol production and function in castration-resistant prostate cancer and ER-positive breast cancer

by Yarong Diana eYin, Melissa eFu, Darby G. Brooke, Daniel M. Heinrich, William A. Denny, William A. Denny, Stephen M. F. Jamieson, Stephen M. F. Jamieson
Published 2014-06-01

Synthesis, structure, and reactivity of the 2,3- and 3,4-N-phenyl imides and the 3-N-phenyl amide of all-cis-cyclopentane-1,2,3,4-tetracarboxylic acid

by N. Guy Billett, Andrew T. Phillis, Lyndsay Main, Brian K. Nicholson, William A. Denny, Michael P. Hay
Published 2005-09-01

Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms

by James P. Dalton, Benedict Uy, Narisa Phummarin, Brent R. Copp, William A. Denny, Simon Swift, Siouxsie Wiles
Published 2016-11-01

Structure-Activity Relationships for the Anaesthetic and Analgaesic Properties of Aromatic Ring-Substituted Ketamine Esters

by Ivaylo V. Dimitrov, Martyn G. Harvey, Logan J. Voss, James W. Sleigh, Michael J. Bickerdike, William A. Denny
Published 2020-06-01

Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain

by Gregory M. Jacobson, Logan J. Voss, Anica Klockars, Steve Bird, Ivo Dimitrov, William A. Denny, Pawel K. Olszewski, James W. Sleigh, Martyn G. Harvey
Published 2019-04-01

Synthetic Studies to Help Elucidate the Metabolism of the Preclinical Candidate TBAJ-876—A Less Toxic and More Potent Analogue of Bedaquiline

by Peter J. Choi, Daniel Conole, Hamish S. Sutherland, Adrian Blaser, Amy S.T. Tong, Christopher B. Cooper, Anna M. Upton, Brian D. Palmer, William A. Denny
Published 2020-03-01

Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents

by Ayesha Zafar, Lisa I. Pilkington, Natalie A. Haverkate, Michelle van Rensburg, Euphemia Leung, Sisira Kumara, William A. Denny, David Barker, Ali Alsuraifi, Clare Hoskins, Jóhannes Reynisson
Published 2018-01-01

The Use of Heptamethine Cyanine Dyes as Drug-Conjugate Systems in the Treatment of Primary and Metastatic Brain Tumors

by Elizabeth Cooper, Elizabeth Cooper, Peter J. Choi, William A. Denny, Jiney Jose, Mike Dragunow, Mike Dragunow, Mike Dragunow, Thomas I.-H. Park, Thomas I.-H. Park
Published 2021-06-01

Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria

by Zhijun Zhuang, Dawei Wan, Jun Ding, Shijie He, Qian Zhang, Xiaomei Wang, Ying Yuan, Yu Lu, Charles Z. Ding, Anthony Simon Lynch, Anna M. Upton, Christopher B. Cooper, William A. Denny, Zhenkun Ma
Published 2020-05-01

Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity

by Chris P. Guise, Maria R. Abbattista, Robert F. Anderson, Dan Li, Rana Taghipouran, Angela Tsai, Su Jung Lee, Jeff B. Smaill, William A. Denny, Michael P. Hay, William R. Wilson, Kevin O. Hicks, Adam V. Patterson
Published 2020-10-01

The Drug Vehicle and Solvent N-Methylpyrrolidone Is an Immunomodulator and Antimyeloma Compound

by Jake Shortt, Andy K. Hsu, Benjamin P. Martin, Karen Doggett, Geoffrey M. Matthews, Maria A. Doyle, Jason Ellul, Tina E. Jockel, Daniel M. Andrews, Simon J. Hogg, Andrea Reitsma, David Faulkner, P. Leif Bergsagel, Marta Chesi, Joan K. Heath, William A. Denny, Philip E. Thompson, Paul J. Neeson, David S. Ritchie, Grant A. McArthur, Ricky W. Johnstone
Published 2014-05-01