Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.

by Sandra M Saldana, Heng-Huan Lee, Frank J Lowery, Yekaterina B Khotskaya, Weiya Xia, Chenyu Zhang, Shih-Shin Chang, Chao-Kai Chou, Patricia S Steeg, Dihua Yu, Mien-Chie Hung
Published 2013-01-01

A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing

by Ruoji Zhou, An Xu, Donghui Wang, Dandan Zhu, Helen Mata, Zijun Huo, Jian Tu, Mo Liu, Alaa M.T. Mohamed, Brittany E. Jewell, Julian Gingold, Weiya Xia, Pulivarthi H. Rao, Mien-Chie Hung, Ruiying Zhao, Dung-Fang Lee
Published 2018-03-01

Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation

by Brittany E. Jewell, Mo Liu, Linchao Lu, Ruoji Zhou, Jian Tu, Dandan Zhu, Zijun Huo, An Xu, Donghui Wang, Helen Mata, Weidong Jin, Weiya Xia, Pulivarthi H. Rao, Ruiying Zhao, Mien-Chie Hung, Lisa L. Wang, Dung-Fang Lee
Published 2018-12-01

Characterization of novel neutralizing mouse monoclonal antibody JM1-24-3 developed against MUC18 in metastatic melanoma

by Runhua Feng, Yuling Wang, Vijaya Ramachandran, Qinhong Ma, Matthew M. May, Ming Li, Joe X. Zhou, Xiang Xu, Kejing Xu, Shenying Fang, Weiya Xia, Dawen Sui, Huey Liu, Xiaolian Gao, Victor Prieto, Stephen C. Blacklow, Mason Lu, Jeffrey E. Lee
Published 2020-12-01

Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing

by An Xu, Ruoji Zhou, Jian Tu, Zijun Huo, Dandan Zhu, Donghui Wang, Julian A. Gingold, Helen Mata, Pulivarthi H. Rao, Mo Liu, Alaa M.T. Mohamed, Celine Shuet Lin Kong, Brittany E. Jewell, Weiya Xia, Ruiying Zhao, Mien-Chie Hung, Dung-Fang Lee
Published 2018-05-01

PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression

by Mi Kyung Park, Yixin Yao, Weiya Xia, Stephanie Rebecca Setijono, Jae Hwan Kim, Isabelle K. Vila, Hui-Hsuan Chiu, Yun Wu, Enrique González Billalabeitia, Min Gyu Lee, Robert G. Kalb, Mien-Chie Hung, Pier Paolo Pandolfi, Su Jung Song, Min Sup Song
Published 2019-02-01

STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion

by Jung-Mao Hsu, Weiya Xia, Yi-Hsin Hsu, Li-Chuan Chan, Wen-Hsuan Yu, Jong-Ho Cha, Chun-Te Chen, Hsin-Wei Liao, Chu-Wei Kuo, Kay-Hooi Khoo, Jennifer L. Hsu, Chia-Wei Li, Seung-Oe Lim, Shih-Shin Chang, Yi-Chun Chen, Guo-xin Ren, Mien-Chie Hung
Published 2018-05-01

CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

by Lei Nie, Yongkun Wei, Fei Zhang, Yi-Hsin Hsu, Li-Chuan Chan, Weiya Xia, Baozhen Ke, Cihui Zhu, Rong Deng, Jun Tang, Jun Yao, Yu-Yi Chu, Xixi Zhao, Ye Han, Junwei Hou, Longfei Huo, How-Wen Ko, Wan-Chi Lin, Hirohito Yamaguchi, Jung-Mao Hsu, Yi Yang, Dean N. Pan, Jennifer L. Hsu, Celina G. Kleer, Nancy E. Davidson, Gabriel N. Hortobagyi, Mien-Chie Hung
Published 2019-11-01

Author Correction: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

by Lei Nie, Yongkun Wei, Fei Zhang, Yi-Hsin Hsu, Li-Chuan Chan, Weiya Xia, Baozhen Ke, Cihui Zhu, Rong Deng, Jun Tang, Jun Yao, Yu-Yi Chu, Xixi Zhao, Ye Han, Junwei Hou, Longfei Huo, How-Wen Ko, Wan-Chi Lin, Hirohito Yamaguchi, Jung-Mao Hsu, Yi Yang, Dean N. Pan, Jennifer L. Hsu, Celina G. Kleer, Nancy E. Davidson, Gabriel N. Hortobagyi, Mien-Chie Hung
Published 2020-01-01

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

by Chia-Wei Li, Seung-Oe Lim, Weiya Xia, Heng-Huan Lee, Li-Chuan Chan, Chu-Wei Kuo, Kay-Hooi Khoo, Shih-Shin Chang, Jong-Ho Cha, Taewan Kim, Jennifer L. Hsu, Yun Wu, Jung-Mao Hsu, Hirohito Yamaguchi, Qingqing Ding, Yan Wang, Jun Yao, Cheng-Chung Lee, Hsing-Ju Wu, Aysegul A. Sahin, James P. Allison, Dihua Yu, Gabriel N. Hortobagyi, Mien-Chie Hung
Published 2016-08-01

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

by Heng-Huan Lee, Ying-Nai Wang, Wen-Hao Yang, Weiya Xia, Yongkun Wei, Li-Chuan Chan, Yu-Han Wang, Zhou Jiang, Shouping Xu, Jun Yao, Yufan Qiu, Yi-Hsin Hsu, Wei-Lun Hwang, Meisi Yan, Jong-Ho Cha, Jennifer L. Hsu, Jia Shen, Yuanqing Ye, Xifeng Wu, Ming-Feng Hou, Lin-Ming Tseng, Shao-Chun Wang, Mei-Ren Pan, Chin-Hua Yang, Yuan-Liang Wang, Hirohito Yamaguchi, Da Pang, Gabriel N. Hortobagyi, Dihua Yu, Mien-Chie Hung
Published 2021-05-01