An Intellectual Disability-Related Missense Mutation in Rac1 Prevents LTP Induction

by Chen Tian, Yuni Kay, Anastasiia Sadybekov, Anastasiia Sadybekov, Sadhna Rao, Vsevolod Katritch, Vsevolod Katritch, Vsevolod Katritch, Bruce E. Herring, Bruce E. Herring
Published 2018-07-01

Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells

by Lisa Seidel, Barbara Zarzycka, Saheem A Zaidi, Vsevolod Katritch, Irene Coin
Published 2017-08-01

An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio

by Anastasiia Sadybekov, Chen Tian, Cosimo Arnesano, Vsevolod Katritch, Bruce E. Herring
Published 2017-09-01

Computational design of thermostabilizing point mutations for G protein-coupled receptors

by Petr Popov, Yao Peng, Ling Shen, Raymond C Stevens, Vadim Cherezov, Zhi-Jie Liu, Vsevolod Katritch
Published 2018-06-01

High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment.

by Theresa Tiefenbrunn, Wei Liu, Ying Chen, Vsevolod Katritch, C David Stout, James A Fee, Vadim Cherezov
Published 2011-01-01

Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ‑OR Agonist

by Jeremy J. Roach, Yusuke Sasano, Cullen L. Schmid, Saheem Zaidi, Vsevolod Katritch, Raymond C. Stevens, Laura M. Bohn, Ryan A. Shenvi
Published 2017-12-01

Structure-based discovery of potent and selective melatonin receptor agonists

by Nilkanth Patel, Xi Ping Huang, Jessica M Grandner, Linda C Johansson, Benjamin Stauch, John D McCorvy, Yongfeng Liu, Bryan Roth, Vsevolod Katritch
Published 2020-03-01

Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR

by Arman A. Sadybekov, Rebecca L. Brouillette, Egor Marin, Anastasiia V. Sadybekov, Aleksandra Luginina, Anastasiia Gusach, Alexey Mishin, Élie Besserer-Offroy, Jean-Michel Longpré, Valentin Borshchevskiy, Vadim Cherezov, Philippe Sarret, Vsevolod Katritch
Published 2020-12-01

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

by Nairie Michaelian, Anastasiia Sadybekov, Élie Besserer-Offroy, Gye Won Han, Harini Krishnamurthy, Beata A. Zamlynny, Xavier Fradera, Phieng Siliphaivanh, Jeremy Presland, Kerrie B. Spencer, Stephen M. Soisson, Petr Popov, Philippe Sarret, Vsevolod Katritch, Vadim Cherezov
Published 2021-05-01

In vitro expression and analysis of the 826 human G protein-coupled receptors

by Xuechen Lv, Junlin Liu, Qiaoyun Shi, Qiwen Tan, Dong Wu, John J. Skinner, Angela L. Walker, Lixia Zhao, Xiangxiang Gu, Na Chen, Lu Xue, Pei Si, Lu Zhang, Zeshi Wang, Vsevolod Katritch, Zhi-jie Liu, Raymond C. Stevens
Published 2016-04-01

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

by Anastasiia Gusach, Aleksandra Luginina, Egor Marin, Rebecca L. Brouillette, Élie Besserer-Offroy, Jean-Michel Longpré, Andrii Ishchenko, Petr Popov, Nilkanth Patel, Taku Fujimoto, Toru Maruyama, Benjamin Stauch, Margarita Ergasheva, Daria Romanovskaia, Anastasiia Stepko, Kirill Kovalev, Mikhail Shevtsov, Valentin Gordeliy, Gye Won Han, Vsevolod Katritch, Valentin Borshchevskiy, Philippe Sarret, Alexey Mishin, Vadim Cherezov
Published 2019-12-01

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

by Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, András Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar
Published 2021-02-01