Computational design of thermostabilizing point mutations for G protein-coupled receptors

by Petr Popov, Yao Peng, Ling Shen, Raymond C Stevens, Vadim Cherezov, Zhi-Jie Liu, Vsevolod Katritch
Published 2018-06-01

High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment.

by Theresa Tiefenbrunn, Wei Liu, Ying Chen, Vsevolod Katritch, C David Stout, James A Fee, Vadim Cherezov
Published 2011-01-01

Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs

by Egor Marin, Aleksandra Luginina, Anastasiia Gusach, Kirill Kovalev, Sergey Bukhdruker, Polina Khorn, Vitaly Polovinkin, Elizaveta Lyapina, Andrey Rogachev, Valentin Gordeliy, Alexey Mishin, Vadim Cherezov, Valentin Borshchevskiy
Published 2020-11-01

Abstract P-4: Robust Method for Background Subtraction in Serial X-ray Diffraction Data

by Egor Marin, Daniil Vakhrameev, Anastasiia Gusach, Aleksandra Luginina, Kirill Kovalev, Wei Liu, Uwe Weierstall, Jaehun Park, Ki Hyun Nam, Cho Yunje, Alexey Mishin, Vadim Cherezov, Valentin Borshchevskiy
Published 2021-06-01

Serial femtosecond crystallography of soluble proteins in lipidic cubic phase

by Raimund Fromme, Andrii Ishchenko, Markus Metz, Shatabdi Roy Chowdhury, Shibom Basu, Sébastien Boutet, Petra Fromme, Thomas A. White, Anton Barty, John C. H. Spence, Uwe Weierstall, Wei Liu, Vadim Cherezov
Published 2015-09-01

Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR

by Arman A. Sadybekov, Rebecca L. Brouillette, Egor Marin, Anastasiia V. Sadybekov, Aleksandra Luginina, Anastasiia Gusach, Alexey Mishin, Élie Besserer-Offroy, Jean-Michel Longpré, Valentin Borshchevskiy, Vadim Cherezov, Philippe Sarret, Vsevolod Katritch
Published 2020-12-01

Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase

by Ming-Yue Lee, James Geiger, Andrii Ishchenko, Gye Won Han, Anton Barty, Thomas A. White, Cornelius Gati, Alexander Batyuk, Mark S. Hunter, Andrew Aquila, Sébastien Boutet, Uwe Weierstall, Vadim Cherezov, Wei Liu
Published 2020-11-01

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

by Nairie Michaelian, Anastasiia Sadybekov, Élie Besserer-Offroy, Gye Won Han, Harini Krishnamurthy, Beata A. Zamlynny, Xavier Fradera, Phieng Siliphaivanh, Jeremy Presland, Kerrie B. Spencer, Stephen M. Soisson, Petr Popov, Philippe Sarret, Vsevolod Katritch, Vadim Cherezov
Published 2021-05-01

Toward G protein-coupled receptor structure-based drug design using X-ray lasers

by Andrii Ishchenko, Benjamin Stauch, Gye Won Han, Alexander Batyuk, Anna Shiriaeva, Chufeng Li, Nadia Zatsepin, Uwe Weierstall, Wei Liu, Eriko Nango, Takanori Nakane, Rie Tanaka, Kensuke Tono, Yasumasa Joti, So Iwata, Isabel Moraes, Cornelius Gati, Vadim Cherezov
Published 2019-11-01

Serial femtosecond X-ray diffraction of enveloped virus microcrystals

by Robert M. Lawrence, Chelsie E. Conrad, Nadia A. Zatsepin, Thomas D. Grant, Haiguang Liu, Daniel James, Garrett Nelson, Ganesh Subramanian, Andrew Aquila, Mark S. Hunter, Mengning Liang, Sébastien Boutet, Jesse Coe, John C. H. Spence, Uwe Weierstall, Wei Liu, Petra Fromme, Vadim Cherezov, Brenda G. Hogue
Published 2015-07-01

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand

by Xianjun Zhang, Fei Zhao, Yiran Wu, Jun Yang, Gye Won Han, Suwen Zhao, Andrii Ishchenko, Lintao Ye, Xi Lin, Kang Ding, Venkatasubramanian Dharmarajan, Patrick R. Griffin, Cornelius Gati, Garrett Nelson, Mark S. Hunter, Michael A. Hanson, Vadim Cherezov, Raymond C. Stevens, Wenfu Tan, Houchao Tao, Fei Xu
Published 2017-05-01

High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source

by Jose M. Martin-Garcia, Lan Zhu, Derek Mendez, Ming-Yue Lee, Eugene Chun, Chufeng Li, Hao Hu, Ganesh Subramanian, David Kissick, Craig Ogata, Robert Henning, Andrii Ishchenko, Zachary Dobson, Shangji Zhang, Uwe Weierstall, John C. H. Spence, Petra Fromme, Nadia A. Zatsepin, Robert F. Fischetti, Vadim Cherezov, Wei Liu
Published 2019-05-01

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

by Anastasiia Gusach, Aleksandra Luginina, Egor Marin, Rebecca L. Brouillette, Élie Besserer-Offroy, Jean-Michel Longpré, Andrii Ishchenko, Petr Popov, Nilkanth Patel, Taku Fujimoto, Toru Maruyama, Benjamin Stauch, Margarita Ergasheva, Daria Romanovskaia, Anastasiia Stepko, Kirill Kovalev, Mikhail Shevtsov, Valentin Gordeliy, Gye Won Han, Vsevolod Katritch, Valentin Borshchevskiy, Philippe Sarret, Alexey Mishin, Vadim Cherezov
Published 2019-12-01

Lipidic cubic phase serial millisecond crystallography using synchrotron radiation

by Przemyslaw Nogly, Daniel James, Dingjie Wang, Thomas A. White, Nadia Zatsepin, Anastasya Shilova, Garrett Nelson, Haiguang Liu, Linda Johansson, Michael Heymann, Kathrin Jaeger, Markus Metz, Cecilia Wickstrand, Wenting Wu, Petra Båth, Peter Berntsen, Dominik Oberthuer, Valerie Panneels, Vadim Cherezov, Henry Chapman, Gebhard Schertler, Richard Neutze, John Spence, Isabel Moraes, Manfred Burghammer, Joerg Standfuss, Uwe Weierstall
Published 2015-03-01

A novel inert crystal delivery medium for serial femtosecond crystallography

by Chelsie E. Conrad, Shibom Basu, Daniel James, Dingjie Wang, Alexander Schaffer, Shatabdi Roy-Chowdhury, Nadia A. Zatsepin, Andrew Aquila, Jesse Coe, Cornelius Gati, Mark S. Hunter, Jason E. Koglin, Christopher Kupitz, Garrett Nelson, Ganesh Subramanian, Thomas A. White, Yun Zhao, James Zook, Sébastien Boutet, Vadim Cherezov, John C. H. Spence, Raimund Fromme, Uwe Weierstall, Petra Fromme
Published 2015-07-01

Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation

by Jose M. Martin-Garcia, Chelsie E. Conrad, Garrett Nelson, Natasha Stander, Nadia A. Zatsepin, James Zook, Lan Zhu, James Geiger, Eugene Chun, David Kissick, Mark C. Hilgart, Craig Ogata, Andrii Ishchenko, Nirupa Nagaratnam, Shatabdi Roy-Chowdhury, Jesse Coe, Ganesh Subramanian, Alexander Schaffer, Daniel James, Gihan Ketwala, Nagarajan Venugopalan, Shenglan Xu, Stephen Corcoran, Dale Ferguson, Uwe Weierstall, John C. H. Spence, Vadim Cherezov, Petra Fromme, Robert F. Fischetti, Wei Liu
Published 2017-07-01