Wild type mesenchymal cells contribute to the lung pathology of lymphangioleiomyomatosis.

by Debbie Clements, Arundhati Dongre, Vera P Krymskaya, Simon R Johnson
Published 2015-01-01

Tumor suppressors TSC1 and TSC2 differentially modulate actin cytoskeleton and motility of mouse embryonic fibroblasts.

by Elena A Goncharova, Melane L James, Tatiana V Kudryashova, Dmitry A Goncharov, Vera P Krymskaya
Published 2014-01-01

Inhibition of Growth of TSC2-Null Cells by a PI3K/mTOR Inhibitor but Not by a Selective MNK1/2 Inhibitor

by Jilly F. Evans, Ryan W. Rue, Alexander R. Mukhitov, Kseniya Obraztsova, Carly J. Smith, Vera P. Krymskaya
Published 2019-12-01

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma.

by Gautam Damera, Kirk M Druey, Philip R Cooper, Vera P Krymskaya, Roy J Soberman, Yassine Amrani, Toshinori Hoshi, Christopher E Brightling, Reynold A Panettieri
Published 2012-01-01

Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells.

by Blanca E Himes, Kseniya Obraztsova, Lurong Lian, Maya Shumyatcher, Ryan Rue, Elena N Atochina-Vasserman, Stella K Hur, Marisa S Bartolomei, Jilly F Evans, Vera P Krymskaya
Published 2018-01-01

Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.

by Doug A Medvetz, Damir Khabibullin, Venkatesh Hariharan, Pat P Ongusaha, Elena A Goncharova, Tanja Schlechter, Thomas N Darling, Ilse Hofmann, Vera P Krymskaya, James K Liao, Hayden Huang, Elizabeth P Henske
Published 2012-01-01

Normalization of Enzyme Expression and Activity Regulating Vitamin A Metabolism Increases RAR-Beta Expression and Reduces Cellular Migration and Proliferation in Diseases Caused by...

by Elhusseiny Mohamed Mahmoud Abdelwahab, Elhusseiny Mohamed Mahmoud Abdelwahab, Judit Bovari-Biri, Judit Bovari-Biri, Gabor Smuk, Tunde Harko, Janos Fillinger, Janos Fillinger, Judit Moldvay, Judit Moldvay, Vera P. Krymskaya, Judit E. Pongracz, Judit E. Pongracz
Published 2021-06-01

Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK

by Elena A. Goncharova, Dmitry A. Goncharov, Melane L. James, Elena N. Atochina-Vasserman, Victoria Stepanova, Seung-Beom Hong, Hua Li, Linda Gonzales, Masaya Baba, W. Marston Linehan, Andrew J. Gow, Susan Margulies, Susan Guttentag, Laura S. Schmidt, Vera P. Krymskaya
Published 2014-04-01

Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells

by Yi Na Dong, Fu-Chun Hsu, Cynthia J. Koziol-White, Victoria Stepanova, Joseph Jude, Andrei Gritsiuta, Ryan Rue, Rosalind Mott, Douglas A. Coulter, Reynold A. Panettieri, Vera P. Krymskaya, Hajime Takano, Elena A. Goncharova, Dmitry A. Goncharov, Douglas B. Cines, David R. Lynch
Published 2021-04-01

mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline

by Kseniya Obraztsova, Maria C. Basil, Ryan Rue, Aravind Sivakumar, Susan M. Lin, Alexander R. Mukhitov, Andrei I. Gritsiuta, Jilly F. Evans, Meghan Kopp, Jeremy Katzen, Annette Robichaud, Elena N. Atochina-Vasserman, Shanru Li, Justine Carl, Apoorva Babu, Michael P. Morley, Edward Cantu, Michael F. Beers, David B. Frank, Edward E. Morrisey, Vera P. Krymskaya
Published 2020-11-01