[Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model.

by Tomomi Nakayama Iwata, Kiyoshi Sugihara, Teiji Wada, Toshinori Agatsuma
Published 2019-01-01

Identification of Physiologically Active Substances as Novel Ligands for MRGPRD

by Makiko Uno, Satoko Nishimura, Keisuke Fukuchi, Yasuyuki Kaneta, Yoko Oda, Hironobu Komori, Shigeki Takeda, Tatsuya Haga, Toshinori Agatsuma, Futoshi Nara
Published 2012-01-01

MRGD, a MAS-related G-protein coupled receptor, promotes tumorigenisis and is highly expressed in lung cancer.

by Satoko Nishimura, Makiko Uno, Yasuyuki Kaneta, Keisuke Fukuchi, Haruyuki Nishigohri, Jun Hasegawa, Hironobu Komori, Shigeki Takeda, Katsuhiko Enomoto, Futoshi Nara, Toshinori Agatsuma
Published 2012-01-01

Anti‐ORAI1 antibody DS‐2741a, a specific CRAC channel blocker, shows ideal therapeutic profiles for allergic disease via suppression of aberrant T‐cell and mast cell activation...

by Anri Aki, Kento Tanaka, Nobumi Nagaoka, Takako Kimura, Daichi Baba, Yoshikuni Onodera, Teiji Wada, Hiroaki Maeda, Toshiyuki Nakanishi, Toshinori Agatsuma, Tomoaki Komai
Published 2020-08-01