Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.

by Arnoud Boot, Jan Oosting, Jaap D H van Eendenburg, Peter J K Kuppen, Hans Morreau, Tom van Wezel
Published 2017-01-01

Allelic Switching of DLX5, GRB10, and SVOPL during Colorectal Cancer Tumorigenesis

by Arnoud Boot, Jan Oosting, Saskia Doorn, Sarah Ouahoud, Marina Ventayol Garcia, Dina Ruano, Hans Morreau, Tom van Wezel
Published 2019-01-01

Targeted Treatment Options of Recurrent Radioactive Iodine Refractory Hürthle Cell Cancer

by Mehtap Derya Aydemirli, Willem Corver, Ruben Beuk, Paul Roepman, Nienke Solleveld-Westerink, Tom van Wezel, Ellen Kapiteijn, Hans Morreau
Published 2019-08-01

Yield and costs of molecular diagnostics on thyroid cytology slides in the Netherlands, adapting the Bethesda classification

by Mehtap Derya Aydemirli, Marieke Snel, Tom vanWezel, Dina Ruano, Christianne M. H. Obbink, Wilbert B. van denHout, Abbey Schepers, Hans Morreau
Published 2021-10-01

Tumor LINE-1 Methylation Level in Association with Survival of Patients with Stage II Colon Cancer

by Marloes Swets, Anniek Zaalberg, Arnoud Boot, Tom van Wezel, Martine A. Frouws, Esther Bastiaannet, Hans Gelderblom, Cornelis J. H. van de Velde, Peter J. K. Kuppen
Published 2016-12-01

Most lung and colon cancer susceptibility genes are pair-wise linked in mice, humans and rats.

by Lei Quan, Alphons P M Stassen, Claudia A L Ruivenkamp, Tom van Wezel, Remond J A Fijneman, Alan Hutson, Neelima Kakarlapudi, Augustinus A M Hart, Peter Demant
Published 2011-02-01

Histological and Somatic Mutational Profiles of Mismatch Repair Deficient Endometrial Tumours of Different Aetiologies

by Neil A. J. Ryan, Thomas D. J. Walker, James Bolton, Natalja ter Haar, Tom Van Wezel, Mark A. Glaire, David N. Church, D. Gareth Evans, Tjalling Bosse, Emma J. Crosbie
Published 2021-09-01

The homeobox gene MEIS1 is methylated in BRAF (p.V600E) mutated colon tumors.

by Ashwin A Dihal, Arnoud Boot, Eddy H van Roon, Melanie Schrumpf, Arantza Fariña-Sarasqueta, Marta Fiocco, Eliane C M Zeestraten, Peter J K Kuppen, Hans Morreau, Tom van Wezel, Judith M Boer
Published 2013-01-01

Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR.

by Ronald van Eijk, Jappe Licht, Melanie Schrumpf, Mehrdad Talebian Yazdi, Dina Ruano, Giusi I Forte, Petra M Nederlof, Maud Veselic, Klaus F Rabe, Jouke T Annema, Vincent Smit, Hans Morreau, Tom van Wezel
Published 2011-03-01

A Phase Ib Clinical Trial of Metformin and Chloroquine in Patients with <i>IDH1</i>-Mutated Solid Tumors

by Mohammed Khurshed, Remco J. Molenaar, Myra E. van Linde, Ron A. Mathôt, Eduard A. Struys, Tom van Wezel, Cornelis J. F. van Noorden, Heinz-Josef Klümpen, Judith V. M. G. Bovée, Johanna W. Wilmink
Published 2021-05-01

Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers.

by Vivian M Spaans, Marjolijn D Trietsch, Stijn Crobach, Ellen Stelloo, Dennis Kremer, Elisabeth M Osse, Natalja T ter Haar, Ronald van Eijk, Susanne Muller, Tom van Wezel, J Baptist Trimbos, Tjalling Bosse, Vincent T H B M Smit, Gert Jan Fleuren
Published 2014-01-01

Genome haploidisation with chromosome 7 retention in oncocytic follicular thyroid carcinoma.

by Willem E Corver, Dina Ruano, Karin Weijers, Wietske C E den Hartog, Merlijn P van Nieuwenhuizen, Noel de Miranda, Ronald van Eijk, Anneke Middeldorp, Ekaterina S Jordanova, Ekaterina S Jordanova, Jan Oosting, Ellen Kapiteijn, Guido Hovens, Jan Smit, Tom van Wezel, Hans Morreau
Published 2012-01-01

The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas

by Lise M. van Wijk, Sylvia Vermeulen, Matty Meijers, Manuela F. van Diest, Natalja T. ter Haar, Marthe M. de Jonge, Nienke Solleveld-Westerink, Tom van Wezel, Dik C. van Gent, Judith R. Kroep, Tjalling Bosse, Katja N. Gaarenstroom, Harry Vrieling, Maaike P.G. Vreeswijk
Published 2020-09-01

The Influence of BRAF and KRAS Mutation Status on the Association between Aspirin Use and Survival after Colon Cancer Diagnosis.

by Martine A Frouws, Marlies S Reimers, Marloes Swets, Esther Bastiaannet, Bianca Prinse, Ronald van Eijk, Valery E P P Lemmens, Myrthe P P van Herk-Sukel, Tom van Wezel, Peter J K Kuppen, Hans Morreau, Cornelis J H van de Velde, Gerrit-Jan Liefers
Published 2017-01-01

Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

by Alan M Pittman, Silvia Naranjo, Sanni E Jalava, Philip Twiss, Yussanne Ma, Bianca Olver, Amy Lloyd, Jayaram Vijayakrishnan, Mobshra Qureshi, Peter Broderick, Tom van Wezel, Hans Morreau, Sari Tuupanen, Lauri A Aaltonen, M Eva Alonso, Miguel Manzanares, Angela Gavilán, Tapio Visakorpi, José Luis Gómez-Skarmeta, Richard S Houlston
Published 2010-09-01

Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome

by Mariano Golubicki, Laia Bonjoch, José G. Acuña-Ochoa, Marcos Díaz-Gay, Jenifer Muñoz, Miriam Cuatrecasas, Teresa Ocaña, Soledad Iseas, Guillermo Mendez, Daniel Cisterna, Stephanie A. Schubert, Maartje Nielsen, Tom van Wezel, Yael Goldberg, Eli Pikarsky, Juan Robbio, Enrique Roca, Antoni Castells, Francesc Balaguer, Marina Antelo, Sergi Castellví-Bel
Published 2020-09-01

Correspondence: SEMA4A variation and risk of colorectal cancer

by Ben Kinnersley, Daniel Chubb, Sara E. Dobbins, Matthew Frampton, Stephan Buch, Maria N. Timofeeva, Sergi Castellví-Bel, Susan M. Farrington, Asta Forsti, Jochen Hampe, Kari Hemminki, Robert M. W. Hofstra, Emma Northwood, Claire Palles, Manuela Pinheiro, Clara Ruiz-Ponte, Clemens Schafmayer, Manuel R. Teixeira, Helga Westers, Tom van Wezel, D. Timothy Bishop, Ian Tomlinson, Malcolm G. Dunlop, Richard S. Houlston
Published 2016-03-01

Association between CASP8 -652 6N del polymorphism (rs3834129) and colorectal cancer risk: results from a multi-centric study.

by Barbara Pardini, Paolo Verderio, Sara Pizzamiglio, Carmela Nici, Maria Valeria Maiorana, Alessio Naccarati, Ludmila Vodickova, Veronika Vymetalkova, Silvia Veneroni, Maria Grazia Daidone, Fernando Ravagnani, Tiziana Bianchi, Luis Bujanda, Angel Carracedo, Antoni Castells, Clara Ruiz-Ponte, Hans Morreau, Kimberley Howarth, Angela Jones, Sergi Castellví-Bel, Li Li, Ian Tomlinson, Tom Van Wezel, Pavel Vodicka, Paolo Radice, Paolo Peterlongo, EPICOLON Consortium
Published 2014-01-01

The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals.

by Anna Abulí, Luis Bujanda, Jenifer Muñoz, Stephan Buch, Clemens Schafmayer, Maria Valeria Maiorana, Silvia Veneroni, Tom van Wezel, Tao Liu, Helga Westers, Clara Esteban-Jurado, Teresa Ocaña, Josep M Piqué, Montserrat Andreu, Rodrigo Jover, Angel Carracedo, Rosa M Xicola, Xavier Llor, Antoni Castells, EPICOLON Consortium, Malcolm Dunlop, Robert Hofstra, Annika Lindblom, Juul Wijnen, Paolo Peterlongo, Jochen Hampe, Clara Ruiz-Ponte, Sergi Castellví-Bel
Published 2014-01-01

Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.

by Anne M L Jansen, Marije A Geilenkirchen, Tom van Wezel, Shantie C Jagmohan-Changur, Dina Ruano, Heleen M van der Klift, Brendy E W M van den Akker, Jeroen F J Laros, Michiel van Galen, Anja Wagner, Tom G W Letteboer, Encarna B Gómez-García, Carli M J Tops, Hans F Vasen, Peter Devilee, Frederik J Hes, Hans Morreau, Juul T Wijnen
Published 2016-01-01