Genome-wide epigenetic cross-talk between DNA methylation and H3K27me3 in zebrafish embryos

by Elisa de la Calle Mustienes, Jose Luis Gómez-Skarmeta, Ozren Bogdanović
Published 2015-12-01

Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns.

by Àlex Robert-Moreno, Silvia Naranjo, Elisa de la Calle-Mustienes, José Luis Gómez-Skarmeta, Berta Alsina
Published 2010-12-01

Assaying Chromatin Accessibility Using ATAC-Seq in Invertebrate Chordate Embryos

by Marta Silvia Magri, Sandra Jiménez-Gancedo, Stephanie Bertrand, Alicia Madgwick, Hector Escrivà, Patrick Lemaire, José Luis Gómez-Skarmeta
Published 2020-01-01

4Cin: A computational pipeline for 3D genome modeling and virtual Hi-C analyses from 4C data.

by Ibai Irastorza-Azcarate, Rafael D Acemel, Juan J Tena, Ignacio Maeso, José Luis Gómez-Skarmeta, Damien P Devos
Published 2018-03-01

Dissecting the transcriptional regulatory properties of human chromosome 16 highly conserved non-coding regions.

by José Luis Royo, Carmen Hidalgo, Yolanda Roncero, María Angeles Seda, Altuna Akalin, Boris Lenhard, Fernando Casares, José Luis Gómez-Skarmeta
Published 2011-01-01

Identification and analysis of conserved cis-regulatory regions of the MEIS1 gene.

by José Luis Royo, José Bessa, Carmen Hidalgo, Ana Fernández-Miñán, Juan J Tena, Yolanda Roncero, José Luis Gómez-Skarmeta, Fernando Casares
Published 2012-01-01

A common copy-number variant within SIRPB1 correlates with human Out-of-Africa migration after genetic drift correction.

by Jose Luis Royo, Joan Valls, Rafael D Acemel, Carlos Gómez-Marin, Mariona Pascual-Pons, Arantxa Lupiañez, Jose Luis Gomez-Skarmeta, Joan Fibla
Published 2018-01-01

Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures

by Raquel García-Pérez, Paula Esteller-Cucala, Glòria Mas, Irene Lobón, Valerio Di Carlo, Meritxell Riera, Martin Kuhlwilm, Arcadi Navarro, Antoine Blancher, Luciano Di Croce, José Luis Gómez-Skarmeta, David Juan, Tomàs Marquès-Bonet
Published 2021-05-01

Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington’s disease mice

by Rafael Alcalá-Vida, Jonathan Seguin, Caroline Lotz, Anne M. Molitor, Ibai Irastorza-Azcarate, Ali Awada, Nezih Karasu, Aurélie Bombardier, Brigitte Cosquer, Jose Luis Gomez Skarmeta, Jean-Christophe Cassel, Anne-Laurence Boutillier, Thomas Sexton, Karine Merienne
Published 2021-01-01

Gene regulatory network architecture in different developmental contexts influences the genetic basis of morphological evolution.

by Sebastian Kittelmann, Alexandra D Buffry, Franziska A Franke, Isabel Almudi, Marianne Yoth, Gonzalo Sabaris, Juan Pablo Couso, Maria D S Nunes, Nicolás Frankel, José Luis Gómez-Skarmeta, Jose Pueyo-Marques, Saad Arif, Alistair P McGregor
Published 2018-05-01

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.

by Melisa Gomez-Velazquez, Claudio Badia-Careaga, Ana Victoria Lechuga-Vieco, Rocio Nieto-Arellano, Juan J Tena, Isabel Rollan, Alba Alvarez, Carlos Torroja, Eva F Caceres, Anna R Roy, Niels Galjart, Paul Delgado-Olguin, Fatima Sanchez-Cabo, Jose Antonio Enriquez, Jose Luis Gomez-Skarmeta, Miguel Manzanares
Published 2017-08-01

A Polymorphic Enhancer near GREM1 Influences Bowel Cancer Risk through Differential CDX2 and TCF7L2 Binding

by Annabelle Lewis, Luke Freeman-Mills, Elisa de la Calle-Mustienes, Rosa María Giráldez-Pérez, Hayley Davis, Emma Jaeger, Martin Becker, Nina C. Hubner, Luan N. Nguyen, Jorge Zeron-Medina, Gareth Bond, Hendrik G. Stunnenberg, Jaime J. Carvajal, Jose Luis Gomez-Skarmeta, Simon Leedham, Ian Tomlinson
Published 2014-08-01

Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders

by Dave T. Gerrard, Andrew A. Berry, Rachel E. Jennings, Matthew J. Birket, Peyman Zarrineh, Myles G. Garstang, Sarah L. Withey, Patrick Short, Sandra Jiménez-Gancedo, Panos N. Firbas, Ian Donaldson, Andrew D. Sharrocks, Karen Piper Hanley, Matthew E. Hurles, José Luis Gomez-Skarmeta, Nicoletta Bobola, Neil A. Hanley
Published 2020-08-01

Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

by Alan M Pittman, Silvia Naranjo, Sanni E Jalava, Philip Twiss, Yussanne Ma, Bianca Olver, Amy Lloyd, Jayaram Vijayakrishnan, Mobshra Qureshi, Peter Broderick, Tom van Wezel, Hans Morreau, Sari Tuupanen, Lauri A Aaltonen, M Eva Alonso, Miguel Manzanares, Angela Gavilán, Tapio Visakorpi, José Luis Gómez-Skarmeta, Richard S Houlston
Published 2010-09-01

Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

by Evelyn N Kouwenhoven, Simon J van Heeringen, Juan J Tena, Martin Oti, Bas E Dutilh, M Eva Alonso, Elisa de la Calle-Mustienes, Leonie Smeenk, Tuula Rinne, Lilian Parsaulian, Emine Bolat, Rasa Jurgelenaite, Martijn A Huynen, Alexander Hoischen, Joris A Veltman, Han G Brunner, Tony Roscioli, Emily Oates, Meredith Wilson, Miguel Manzanares, José Luis Gómez-Skarmeta, Hendrik G Stunnenberg, Marion Lohrum, Hans van Bokhoven, Huiqing Zhou
Published 2010-08-01