Protein engineering strategies for improving the selective methylation of target CpG sites by a dCas9-directed cytosine methyltransferase in bacteria.

by Tina Xiong, Dahlia Rohm, Rachael E Workman, Lauren Roundtree, Carl D Novina, Winston Timp, Marc Ostermeier
Published 2018-01-01

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases

by Tina Xiong, Glenna E. Meister, Rachael E. Workman, Nathaniel C. Kato, Michael J. Spellberg, Fulya Turker, Winston Timp, Marc Ostermeier, Carl D. Novina
Published 2017-07-01