Protein engineering strategies for improving the selective methylation of target CpG sites by a dCas9-directed cytosine methyltransferase in bacteria.

by Tina Xiong, Dahlia Rohm, Rachael E Workman, Lauren Roundtree, Carl D Novina, Winston Timp, Marc Ostermeier
Published 2018-01-01

The lncRNA SLNCR1 Mediates Melanoma Invasion through a Conserved SRA1-like Region

by Karyn Schmidt, Cailin E. Joyce, Frank Buquicchio, Adam Brown, Justin Ritz, Robert J. Distel, Charles H. Yoon, Carl D. Novina
Published 2016-05-01

The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21

by Karyn Schmidt, Johanna S. Carroll, Elaine Yee, Dolly D. Thomas, Leon Wert-Lamas, Steven C. Neier, Gloria Sheynkman, Justin Ritz, Carl D. Novina
Published 2019-05-01

Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor

by Karyn Schmidt, Chase A. Weidmann, Thomas A. Hilimire, Elaine Yee, Breanne M. Hatfield, John S. Schneekloth, Jr., Kevin M. Weeks, Carl D. Novina
Published 2020-01-01

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases

by Tina Xiong, Glenna E. Meister, Rachael E. Workman, Nathaniel C. Kato, Michael J. Spellberg, Fulya Turker, Winston Timp, Marc Ostermeier, Carl D. Novina
Published 2017-07-01

MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells.

by Shuqiang Li, Howell F Moffett, Jun Lu, Lillian Werner, Hao Zhang, Jerome Ritz, Donna Neuberg, Kai W Wucherpfennig, Jennifer R Brown, Carl D Novina
Published 2011-03-01

Feed-forward microprocessing and splicing activities at a microRNA-containing intron.

by Maja M Janas, Mehdi Khaled, Steffen Schubert, Jacob G Bernstein, David Golan, Rosa A Veguilla, David E Fisher, Noam Shomron, Carmit Levy, Carl D Novina
Published 2011-10-01