An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

by Eva Hesping, Tina S. Skinner-Adams, Gillian M. Fisher, Thomas Kurz, Katherine T. Andrews
Published 2020-12-01

Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

by Ming Jang Chua, Dina Robaa, Tina S. Skinner-Adams, Wolfgang Sippl, Katherine T. Andrews
Published 2018-08-01

An image-based Pathogen Box screen identifies new compounds with anti-Giardia activity and highlights the importance of assay choice in phenotypic drug discovery

by Snigdha Tiash, Jake Saunders, Christopher J.S. Hart, John H. Ryan, Andrew G. Riches, Tina S. Skinner-Adams
Published 2020-04-01

A novel in vitro image-based assay identifies new drug leads for giardiasis

by Christopher J.S. Hart, Taylah Munro, Katherine T. Andrews, John H. Ryan, Andrew G. Riches, Tina S. Skinner-Adams
Published 2017-04-01

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A–D

by Brett D. Schwartz, Mark J. Coster, Tina S. Skinner-Adams, Katherine T. Andrews, Jonathan M. White, Rohan A. Davis
Published 2015-09-01

Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum.

by Marcin Poreba, Sheena McGowan, Tina S Skinner-Adams, Katharine R Trenholme, Donald L Gardiner, James C Whisstock, Joyce To, Guy S Salvesen, John P Dalton, Marcin Drag
Published 2012-01-01

Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

by Ming Jang Chua, Megan S.J. Arnold, Weijun Xu, Julien Lancelot, Suzanne Lamotte, Gerald F. Späth, Eric Prina, Raymond J. Pierce, David P. Fairlie, Tina S. Skinner-Adams, Katherine T. Andrews
Published 2017-04-01

Anti-malaria drug development targeting the M1 alanyl and M17 leucyl aminopeptidases

by Karine Thivierge, Rency T. Mathew, Desire M. M. Nsangou, Fabio Da Silva, Sophie Cotton, Tina S. Skinner-Adams, Katharine R. Trenholme, Christopher L. Brown, Colin M. Stack, Donald L. Gardiner, John P. Dalton
Published 2012-06-01

The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment.

by Tina S Skinner-Adams, Alice S Butterworth, Kimberly A Porter, Ronald D'Amico, Fred Sawe, Doug Shaffer, Abraham Siika, Mina C Hosseinipour, Elizabeth Stringer, Judith S Currier, Tsungai Chipato, Robert Salata, Shahin Lockman, Joseph J Eron, Steven R Meshnick, James S McCarthy
Published 2012-01-01