Analysis of the interactome of Schistosoma mansoni histone deacetylase 8.

by Stéphanie Caby, Lucile Pagliazzo, Julien Lancelot, Jean-Michel Saliou, Nicolas Bertheaume, Raymond J Pierce, Emmanuel Roger
Published 2017-11-01

Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni.

by Alvaro Baeza Garcia, Raymond J Pierce, Benjamin Gourbal, Elisabeth Werkmeister, Dominique Colinet, Jean-Marc Reichhart, Colette Dissous, Christine Coustau
Published 2010-09-01

Schistosoma mansoni Sirtuins: characterization and potential as chemotherapeutic targets.

by Julien Lancelot, Stéphanie Caby, Florence Dubois-Abdesselem, Mathieu Vanderstraete, Jacques Trolet, Guilherme Oliveira, Franz Bracher, Manfred Jung, Raymond J Pierce
Published 2013-01-01

Controlled chaos of polymorphic mucins in a metazoan parasite (Schistosoma mansoni) interacting with its invertebrate host (Biomphalaria glabrata).

by Emmanuel Roger, Christoph Grunau, Raymond J Pierce, Hirohisa Hirai, Benjamin Gourbal, Richard Galinier, Rémi Emans, Italo M Cesari, Céline Cosseau, Guillaume Mitta
Published 2008-01-01

Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

by Ming Jang Chua, Megan S.J. Arnold, Weijun Xu, Julien Lancelot, Suzanne Lamotte, Gerald F. Späth, Eric Prina, Raymond J. Pierce, David P. Fairlie, Tina S. Skinner-Adams, Katherine T. Andrews
Published 2017-04-01

A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

by Conrad V. Simoben, Dina Robaa, Alokta Chakrabarti, Karin Schmidtkunz, Martin Marek, Julien Lancelot, Srinivasaraghavan Kannan, Jelena Melesina, Tajith B. Shaik, Raymond J. Pierce, Christophe Romier, Manfred Jung, Wolfgang Sippl
Published 2018-03-01

Epigenetic changes modulate schistosome egg formation and are a novel target for reducing transmission of schistosomiasis.

by Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Eduardo José Lopes Torres, Stephany Caby, Julien Lancelot, Mathieu Vanderstraete, Silviya D Furdas, Manfred Jung, Raymond J Pierce, Marcelo Rosado Fantappié
Published 2014-05-01

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni.

by Martin Marek, Srinivasaraghavan Kannan, Alexander-Thomas Hauser, Marina Moraes Mourão, Stéphanie Caby, Vincent Cura, Diana A Stolfa, Karin Schmidtkunz, Julien Lancelot, Luiza Andrade, Jean-Paul Renaud, Guilherme Oliveira, Wolfgang Sippl, Manfred Jung, Jean Cavarelli, Raymond J Pierce, Christophe Romier
Published 2013-01-01

Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and no...

by Adriana S A Pereira, Murilo S Amaral, Elton J R Vasconcelos, David S Pires, Huma Asif, Lucas F daSilva, David A Morales-Vicente, Vitor C Carneiro, Claudia B Angeli, Giuseppe Palmisano, Marcelo R Fantappie, Raymond J Pierce, João C Setubal, Sergio Verjovski-Almeida
Published 2018-10-01

Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma...

by Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Murilo Sena Amaral, Adriana S A Pereira, Gilbert Oliveira Silveira, David da Silva Pires, Sergio Verjovski-Almeida, Frank J Dekker, Dante Rotili, Antonello Mai, Eduardo José Lopes-Torres, Dina Robaa, Wolfgang Sippl, Raymond J Pierce, M Teresa Borrello, A Ganesan, Julien Lancelot, Silvana Thiengo, Monica Ammon Fernandez, Amanda Roberta Revoredo Vicentino, Marina Moraes Mourão, Fernanda Sales Coelho, Marcelo Rosado Fantappié
Published 2020-07-01