Mechanisms of Dysregulated Antibody Response in Lyme Disease

by Timothy J. Sellati, Dana M. Barberio
Published 2020-10-01

An Immature Myeloid/Myeloid-Suppressor Cell Response Associated with Necrotizing Inflammation Mediates Lethal Pulmonary Tularemia.

by Sivakumar Periasamy, Dorina Avram, Amanda McCabe, Katherine C MacNamara, Timothy J Sellati, Jonathan A Harton
Published 2016-03-01

CD14 signaling restrains chronic inflammation through induction of p38-MAPK/SOCS-dependent tolerance.

by Bikash Sahay, Rebeca L Patsey, Christian H Eggers, Juan C Salazar, Justin D Radolf, Timothy J Sellati
Published 2009-12-01

Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity.

by Anju Singh, Tabassum Rahman, Meenakshi Malik, Anthony J Hickey, Cynthia A Leifer, Karsten R O Hazlett, Timothy J Sellati
Published 2013-01-01

Host-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.

by Tiffany M Zarrella, Anju Singh, Constantine Bitsaktsis, Tabassum Rahman, Bikash Sahay, Paul J Feustel, Edmund J Gosselin, Timothy J Sellati, Karsten R O Hazlett
Published 2011-01-01

Autotransporter-Mediated Display of Complement Receptor Ligands by Gram-Negative Bacteria Increases Antibody Responses and Limits Disease Severity

by Kristen M Holland-Tummillo, Lauren E Shoudy, Donald Steiner, Sudeep Kumar, Sarah J Rosa, Prachi Namjoshi, Anju Singh, Timothy J Sellati, Edmund J Gosselin, Karsten RO Hazlett
Published 2020-05-01

Differential Growth of Francisella tularensis, Which Alters Expression of Virulence Factors, Dominant Antigens, and Surface-Carbohydrate Synthases, Governs the Apparent Virulence o...

by Kristen M. Holland, Sarah J. Rosa, Kolbrun Kristjansdottir, Donald Wolfgeher, Brian J. Franz, Tiffany M. Zarrella, Sudeep Kumar, Raju Sunagar, Anju Singh, Chandra S. Bakshi, Prachi Namjoshi, Eileen M. Barry, Timothy J. Sellati, Stephen J. Kron, Edmund J. Gosselin, Douglas S. Reed, Karsten R. O. Hazlett
Published 2017-06-01