Dynamics of resistance development to imatinib under increasing selection pressure: a combination of mathematical models and in vitro data.

by Benjamin Werner, David Lutz, Tim H Brümmendorf, Arne Traulsen, Stefan Balabanov
Published 2011-01-01

Transient elastography in adult patients with cryptic dyskeratosis congenita reveals subclinical liver fibrosis: a retrospective analysis of the Aachen telomere biology disease reg...

by Mareike Tometten, Martin Kirschner, Susanne Isfort, Marie-Luise Berres, Tim H. Brümmendorf, Fabian Beier
Published 2021-09-01

MicroRNA expression profiles of serum from patients before and after chemotherapy

by Yvonne Diener, Thomas Walenda, Edgar Jost, Tim H. Brümmendorf, Andreas Bosio, Wolfgang Wagner, Ute Bissels
Published 2015-12-01

Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion

by Lijuan Han, Claudia Schubert, Johanna Köhler, Mirle Schemionek, Susanne Isfort, Tim H. Brümmendorf, Steffen Koschmieder, Nicolas Chatain
Published 2016-05-01

Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy

by Benjamin Rolles, Benjamin Rolles, Joao Gorgulho, Mareike Tometten, Mareike Tometten, Christoph Roderburg, Margherita Vieri, Margherita Vieri, Anne Abels, Anne Abels, Mihael Vucur, Felix Heymann, Frank Tacke, Tim H. Brümmendorf, Tim H. Brümmendorf, Tom Luedde, Fabian Beier, Fabian Beier, Sven H. Loosen
Published 2021-08-01

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

by Benjamin Werner, Fabian Beier, Sebastian Hummel, Stefan Balabanov, Lisa Lassay, Thorsten Orlikowsky, David Dingli, Tim H Brümmendorf, Arne Traulsen
Published 2015-10-01

Revesz syndrome revisited

by Michael Karremann, Eva Neumaier-Probst, Frank Schlichtenbrede, Fabian Beier, Tim H. Brümmendorf, Friedrich W. Cremer, Peter Bader, Matthias Dürken
Published 2020-10-01

Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Cong...

by Margherita Vieri, Martin Kirschner, Mareike Tometten, Anne Abels, Benjamin Rolles, Susanne Isfort, Jens Panse, Tim H. Brümmendorf, Fabian Beier
Published 2020-09-01

Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells.

by Richard K Lubberich, Thomas Walenda, Tamme W Goecke, Klaus Strathmann, Susanne Isfort, Tim H Brümmendorf, Steffen Koschmieder, Wolfgang Wagner
Published 2018-01-01

Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas

by Monica S. Ventura Ferreira, Martina Crysandt, Till Braunschweig, Edgar Jost, Barbara Voss, Anne-Sophie Bouillon, Ruth Knuechel, Tim H. Brümmendorf, Fabian Beier
Published 2018-02-01

MicroRNAs and Metabolites in Serum Change after Chemotherapy: Impact on Hematopoietic Stem and Progenitor Cells.

by Thomas Walenda, Yvonne Diener, Edgar Jost, Elizabeth Morin-Kensicki, Tamme W Goecke, Andreas Bosio, Björn Rath, Tim H Brümmendorf, Ute Bissels, Wolfgang Wagner
Published 2015-01-01

Serum after autologous transplantation stimulates proliferation and expansion of human hematopoietic progenitor cells.

by Thomas Walenda, Gudrun Bokermann, Edgar Jost, Oliver Galm, Anne Schellenberg, Carmen M Koch, Daniela M Piroth, Wolf Drescher, Tim H Brümmendorf, Wolfgang Wagner
Published 2011-01-01

CRISPR/Cas9 mediated CXCL4 knockout in human iPS cells of polycythemia vera patient with JAK2 V617F mutation

by Janik Boehnke, Salim Atakhanov, Marcelo A.S. Toledo, Herdit M. Schüler, Stephanie Sontag, Nicolas Chatain, Steffen Koschmieder, Tim H. Brümmendorf, Rafael Kramann, Martin Zenke
Published 2021-08-01

Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

by Daniel Benten, Gunhild Keller, Alexander Quaas, Jorg Schrader, Artur Gontarewicz, Stefan Balabanov, Melanie Braig, Henning Wege, Jurgen Moll, Ansgar W. Lohse, Tim H. Brummendorf
Published 2009-09-01

Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta

by Mónica S. Ventura Ferreira, Michaela Bienert, Katrin Müller, Björn Rath, Tamme Goecke, Christian Opländer, Till Braunschweig, Petra Mela, Tim H. Brümmendorf, Fabian Beier, Sabine Neuss
Published 2018-02-01

Combination of a proteomics approach and reengineering of meso scale network models for prediction of mode-of-action for tyrosine kinase inhibitors.

by Stefan Balabanov, Thomas Wilhelm, Simone Venz, Gunhild Keller, Christian Scharf, Heike Pospisil, Melanie Braig, Christine Barett, Carsten Bokemeyer, Reinhard Walther, Tim H Brümmendorf, Andreas Schuppert
Published 2013-01-01

Infliximab therapy together with tyrosine kinase inhibition targets leukemic stem cells in chronic myeloid leukemia

by Oliver Herrmann, Maja Kim Kuepper, Marlena Bütow, Ivan G. Costa, Iris Appelmann, Fabian Beier, Tom Luedde, Till Braunschweig, Steffen Koschmieder, Tim H. Brümmendorf, Mirle Schemionek
Published 2019-07-01

A three-gene expression-based risk score can refine the European LeukemiaNet AML classification

by Stefan Wilop, Wen-Chien Chou, Edgar Jost, Martina Crysandt, Jens Panse, Ming-Kai Chuang, Tim H. Brümmendorf, Wolfgang Wagner, Hwei-Fang Tien, Behzad Kharabi Masouleh
Published 2016-09-01

Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha

by Claudia Schubert, Manuel Allhoff, Stefan Tillmann, Tiago Maié, Ivan G. Costa, Daniel B. Lipka, Mirle Schemionek, Kristina Feldberg, Julian Baumeister, Tim H. Brümmendorf, Nicolas Chatain, Steffen Koschmieder
Published 2019-04-01

Epigenetic Clocks Are Not Accelerated in COVID-19 Patients

by Julia Franzen, Selina Nüchtern, Vithurithra Tharmapalan, Margherita Vieri, Miloš Nikolić, Yang Han, Paul Balfanz, Nikolaus Marx, Michael Dreher, Tim H. Brümmendorf, Edgar Dahl, Fabian Beier, Wolfgang Wagner
Published 2021-08-01