Accelerated Development of Rod Photoreceptors in Retinal Organoids Derived from Human Pluripotent Stem Cells by Supplementation with 9-cis Retinal

by Ryan A. Kelley, Holly Y. Chen, Anand Swaroop, Tiansen Li
Published 2020-06-01

Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a

by Chunqiao Liu, Chen Lin, Chun Gao, Helen May-Simera, Anand Swaroop, Tiansen Li
Published 2014-09-01

Increased light exposure alleviates one form of photoreceptor degeneration marked by elevated calcium in the dark.

by Xiaoqing Liu, Basil S Pawlyk, Michael Adamian, Elena V Olshevskaya, Alexander M Dizhoor, Clint L Makino, Tiansen Li
Published 2009-12-01

Selection and characterization of specific nanobody against bovine virus diarrhea virus (BVDV) E2 protein.

by Tiansen Li, Meiling Huang, Hongran Xiao, Guoqi Zhang, Jinhua Ding, Peng Wu, Hui Zhang, Jinliang Sheng, Chuangfu Chen
Published 2017-01-01

Brucella Melitensis 16M Regulates the Effect of AIR Domain on Inflammatory Factors, Autophagy, and Apoptosis in Mouse Macrophage through the ROS Signaling Pathway.

by Tiansen Li, Yafang Xu, Laizhen Liu, Meiling Huang, Zhen Wang, Zhixia Tong, Hui Zhang, Fei Guo, Chuangfu Chen
Published 2016-01-01

Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss.

by Jun Yang, Xiaoqing Liu, Yun Zhao, Michael Adamian, Basil Pawlyk, Xun Sun, D Randy McMillan, M Charles Liberman, Tiansen Li
Published 2010-05-01

Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo

by Matthew J. Brooks, Holly Y. Chen, Ryan A. Kelley, Anupam K. Mondal, Kunio Nagashima, Natalia De Val, Tiansen Li, Vijender Chaitankar, Anand Swaroop
Published 2019-11-01

A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration

by Suddhasil Mookherjee, Holly Yu Chen, Kevin Isgrig, Wenhan Yu, Suja Hiriyanna, Rivka Levron, Tiansen Li, Peter Colosi, Wade Chien, Anand Swaroop, Zhijian Wu
Published 2018-10-01

Outer Membrane Protein 25 of Brucella Activates Mitogen-Activated Protein Kinase Signal Pathway in Human Trophoblast Cells

by Jing Zhang, Yu Zhang, Zhiqiang Li, Jing Liu, Xuehua Shao, Changxin Wu, Yong Wang, Kaisheng Wang, Tiansen Li, Laizhen Liu, Chuangfu Chen, Hui Zhang
Published 2017-12-01

Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice

by Wenhan Yu, Suddhasil Mookherjee, Vijender Chaitankar, Suja Hiriyanna, Jung-Woong Kim, Matthew Brooks, Yasaman Ataeijannati, Xun Sun, Lijin Dong, Tiansen Li, Anand Swaroop, Zhijian Wu
Published 2017-03-01

Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration.

by Passley Hargrove-Grimes, Anupam K Mondal, Jessica Gumerson, Jacob Nellissery, Angel M Aponte, Linn Gieser, Haohua Qian, Robert N Fariss, Juan S Bonifacino, Tiansen Li, Anand Swaroop
Published 2020-12-01

The Complete Genome of Brucella Suis 019 Provides Insights on Cross-Species Infection

by Yuanzhi Wang, Zhen Wang, Xin Chen, Hui Zhang, Fei Guo, Ke Zhang, Hanping Feng, Wenyi Gu, Changxin Wu, Lei Ma, Tiansen Li, Chuangfu Chen, Shan Gao
Published 2016-01-01

Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15.

by Debra A Thompson, Naheed W Khan, Mohammad I Othman, Bo Chang, Lin Jia, Garrett Grahek, Zhijian Wu, Suja Hiriyanna, Jacob Nellissery, Tiansen Li, Hemant Khanna, Peter Colosi, Anand Swaroop, John R Heckenlively
Published 2012-01-01

Loss of MACF1 Abolishes Ciliogenesis and Disrupts Apicobasal Polarity Establishment in the Retina

by Helen L. May-Simera, Jessica D. Gumerson, Chun Gao, Maria Campos, Stephanie M. Cologna, Tina Beyer, Karsten Boldt, Koray D. Kaya, Nisha Patel, Friedrich Kretschmer, Matthew W. Kelley, Ronald S. Petralia, Megan G. Davey, Tiansen Li
Published 2016-10-01

In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations

by Hiroko Shimada, Quanlong Lu, Christine Insinna-Kettenhofen, Kunio Nagashima, Milton A. English, Elizabeth M. Semler, Jacklyn Mahgerefteh, Artur V. Cideciyan, Tiansen Li, Brian P. Brooks, Meral Gunay-Aygun, Samuel G. Jacobson, Tiziana Cogliati, Christopher J. Westlake, Anand Swaroop
Published 2017-07-01