An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria.

by Borko Amulic, Ali Salanti, Thomas Lavstsen, Morten A Nielsen, Kirk W Deitsch
Published 2009-01-01

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

by Estela Shabani, Benjamin Hanisch, Robert O. Opoka, Thomas Lavstsen, Chandy C. John
Published 2017-10-01

Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.

by Thomas S Rask, Daniel A Hansen, Thor G Theander, Anders Gorm Pedersen, Thomas Lavstsen
Published 2010-09-01

Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies

by Charlotte Harmsen, Louise Turner, Susan Thrane, Adam F. Sander, Thor G. Theander, Thomas Lavstsen
Published 2020-03-01

The structural basis for CD36 binding by the malaria parasite

by Fu-Lien Hsieh, Louise Turner, Jani Reddy Bolla, Carol V. Robinson, Thomas Lavstsen, Matthew K. Higgins
Published 2016-09-01

Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers.

by Louise Turner, Christian W Wang, Thomas Lavstsen, Steven B Mwakalinga, Robert W Sauerwein, Cornelus C Hermsen, Thor G Theander
Published 2011-01-01

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates.

by Adam F Sander, Ali Salanti, Thomas Lavstsen, Morten A Nielsen, Pamela Magistrado, John Lusingu, Nicaise Tuikue Ndam, David E Arnot
Published 2009-08-01

Sickle-trait hemoglobin reduces adhesion to both CD36 and EPCR by Plasmodium falciparum-infected erythrocytes.

by Jens E V Petersen, Joseph W Saelens, Elizabeth Freedman, Louise Turner, Thomas Lavstsen, Rick M Fairhurst, Mahamadou Diakité, Steve M Taylor
Published 2021-06-01

Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein

by Natalie M. Barber, Clinton K. Y. Lau, Louise Turner, Gareth Watson, Susan Thrane, John P. A. Lusingu, Thomas Lavstsen, Matthew K. Higgins
Published 2021-02-01

Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression.

by Nicaise Tuikue Ndam, Emmanuel Bischoff, Caroline Proux, Thomas Lavstsen, Ali Salanti, Juliette Guitard, Morten A Nielsen, Jean-Yves Coppée, Alioune Gaye, Thor Theander, Peter H David, Philippe Deloron
Published 2008-03-01

Cerebral malaria is associated with differential cytoadherence to brain endothelial cells

by Janet Storm, Jakob S Jespersen, Karl B Seydel, Tadge Szestak, Maurice Mbewe, Ngawina V Chisala, Patricia Phula, Christian W Wang, Terrie E Taylor, Christopher A Moxon, Thomas Lavstsen, Alister G Craig
Published 2019-02-01

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites.

by Philip Bejon, Louise Turner, Thomas Lavstsen, Gerald Cham, Ally Olotu, Chris J Drakeley, Marc Lievens, Johan Vekemans, Barbara Savarese, John Lusingu, Lorenz von Seidlein, Peter C Bull, Kevin Marsh, Thor G Theander
Published 2011-01-01

Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin.

by Gwladys I Bertin, Thomas Lavstsen, François Guillonneau, Justin Doritchamou, Christian W Wang, Jakob S Jespersen, Sem Ezimegnon, Nadine Fievet, Maroufou J Alao, Francis Lalya, Achille Massougbodji, Nicaise Tuikue Ndam, Thor G Theander, Philippe Deloron
Published 2013-01-01

Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1.

by Louise Joergensen, Dominique C Bengtsson, Anja Bengtsson, Elena Ronander, Sanne S Berger, Louise Turner, Michael B Dalgaard, Gerald K K Cham, Michala E Victor, Thomas Lavstsen, Thor G Theander, David E Arnot, Anja T R Jensen
Published 2010-09-01

Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.

by Sanne S Berger, Louise Turner, Christian W Wang, Jens E V Petersen, Maria Kraft, John P A Lusingu, Bruno Mmbando, Andrea M Marquard, Dominique B A C Bengtsson, Lars Hviid, Morten A Nielsen, Thor G Theander, Thomas Lavstsen
Published 2013-01-01

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression.

by Anna Bachmann, Ellen Bruske, Ralf Krumkamp, Louise Turner, J Stephan Wichers, Michaela Petter, Jana Held, Michael F Duffy, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Bertrand Lell, Thomas Lavstsen, Matthias Frank, Benjamin Mordmüller, Egbert Tannich
Published 2019-07-01

Meta-analysis of Plasmodium falciparumvar Signatures Contributing to Severe Malaria in African Children and Indian Adults

by Fergal Duffy, Maria Bernabeu, Prasad H. Babar, Anne Kessler, Christian W. Wang, Marina Vaz, Laura Chery, Wilson L. Mandala, Stephen J. Rogerson, Terrie E. Taylor, Karl B. Seydel, Thomas Lavstsen, Edwin Gomes, Kami Kim, John Lusingu, Pradipsinh K. Rathod, John D. Aitchison, Joseph D. Smith
Published 2019-04-01

Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

by Kaituo Wang, Robert Dagil, Thomas Lavstsen, Sandeep K. Misra, Charlotte B. Spliid, Yong Wang, Tobias Gustavsson, Daniel R. Sandoval, Elena Ethel Vidal-Calvo, Swati Choudhary, Mette Ø Agerbaek, Kresten Lindorff-Larsen, Morten A. Nielsen, Thor G. Theander, Joshua S. Sharp, Thomas Mandel Clausen, Pontus Gourdon, Ali Salanti
Published 2021-05-01

Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria.

by Ariel Magallón-Tejada, Sónia Machevo, Pau Cisteró, Thomas Lavstsen, Pedro Aide, Mercedes Rubio, Alfons Jiménez, Louise Turner, Aida Valmaseda, Himanshu Gupta, Briegel De Las Salas, Inacio Mandomando, Christian W Wang, Jens E V Petersen, Jose Muñoz, Joaquim Gascón, Eusebio Macete, Pedro L Alonso, Chetan E Chitnis, Quique Bassat, Alfredo Mayor
Published 2016-11-01

Associations between IgG reactivity to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens and Burkitt lymphoma in Ghana and Uganda case-control studiesResearch...

by Andriy Derkach, Isaac Otim, Ruth M. Pfeiffer, Olusegun O. Onabajo, Ismail D. Legason, Hadijah Nabalende, Martin D. Ogwang, Patrick Kerchan, Ambrose O. Talisuna, Leona W. Ayers, Steven J. Reynolds, Francis Nkrumah, Janet Neequaye, Kishor Bhatia, Thor G. Theander, Ludmila Prokunina-Olsson, Louise Turner, James J. Goedert, Thomas Lavstsen, Sam M. Mbulaiteye
Published 2019-01-01