The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model.

by Shuhei Kobayashi, Akira Hara, Takayuki Isagawa, Ichiro Manabe, Kiyoshi Takeda, Takashi MaruYama
Published 2014-01-01

Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription

by Yumiko Oishi, Shinichiro Hayashi, Takayuki Isagawa, Motohiko Oshima, Atsushi Iwama, Shigeki Shimba, Hitoshi Okamura, Ichiro Manabe
Published 2017-08-01

DNA methylation profiling of embryonic stem cell differentiation into the three germ layers.

by Takayuki Isagawa, Genta Nagae, Nobuaki Shiraki, Takanori Fujita, Noriko Sato, Shumpei Ishikawa, Shoen Kume, Hiroyuki Aburatani
Published 2011-01-01

GADD45β Determines Chemoresistance and Invasive Growth of Side Population Cells of Human Embryonic Carcinoma

by Toshihiko Inowa, Keiichi Hishikawa, Yumi Matsuzaki, Takayuki Isagawa, Takumi Takeuchi, Hiroyuki Aburatani, Tadaichi Kitamura, Toshiro Fujita
Published 2010-01-01

Establishment of Novel Protein Interaction Assays between Sin3 and REST Using Surface Plasmon Resonance and Time-Resolved Fluorescence Energy Transfer

by Masamitsu Harada, Jun Nagai, Riho Kurata, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Published 2021-02-01

Stepwise development of hematopoietic stem cells from embryonic stem cells.

by Kenji Matsumoto, Takayuki Isagawa, Toshinobu Nishimura, Takunori Ogaeri, Koji Eto, Satsuki Miyazaki, Jun-ichi Miyazaki, Hiroyuki Aburatani, Hiromitsu Nakauchi, Hideo Ema
Published 2009-01-01

Febuxostat, a Xanthine Oxidase Inhibitor, Decreased Macrophage Matrix Metalloproteinase Expression in Hypoxia

by Shuoyu Wei, Takayuki Isagawa, Masamichi Eguchi, Daisuke Sato, Hiroto Tsukano, Keishi Miyata, Yuichi Oike, Norihiko Takeda, Satoshi Ikeda, Hiroaki Kawano, Koji Maemura
Published 2020-11-01

The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells.

by Osamu Takase, Masahiro Yoshikawa, Mana Idei, Junichi Hirahashi, Toshiro Fujita, Tsuyoshi Takato, Takayuki Isagawa, Genta Nagae, Hirofumi Suemori, Hiroyuki Aburatani, Keiichi Hishikawa
Published 2013-01-01

Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells.

by Masashi Yukawa, Tomohiko Akiyama, Vedran Franke, Nathan Mise, Takayuki Isagawa, Yutaka Suzuki, Masataka G Suzuki, Kristian Vlahovicek, Kuniya Abe, Hiroyuki Aburatani, Fugaku Aoki
Published 2014-01-01

Establishment of Novel High-Standard Chemiluminescent Assay for NTPase in Two Protozoans and Its High-Throughput Screening

by Masamitsu Harada, Jun Nagai, Riho Kurata, Kenji Shimizu, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Jun Ishihara, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Published 2020-03-01

Therapeutic targeting of mitochondrial ROS ameliorates murine model of volume overload cardiomyopathy

by Kenichi Okamura, Yu Nakagama, Norihiko Takeda, Katsura Soma, Tatsuyuki Sato, Takayuki Isagawa, Yasutoshi Kido, Masaya Sakamoto, Ichiro Manabe, Yasutaka Hirata, Issei Komuro, Minoru Ono
Published 2019-09-01

Novel Reporter System Monitoring IL-18 Specific Signaling Can Be Applied to High-Throughput Screening

by Riho Kurata, Kenji Shimizu, Xiaofeng Cui, Masamitsu Harada, Takayuki Isagawa, Hiroaki Semba, Jun Ishihara, Koji Yamada, Jun Nagai, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Published 2020-01-01

Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis

by Ewelina Krzywinska, Chahrazade Kantari-Mimoun, Yann Kerdiles, Michal Sobecki, Takayuki Isagawa, Dagmar Gotthardt, Magali Castells, Johannes Haubold, Corinne Millien, Thomas Viel, Bertrand Tavitian, Norihiko Takeda, Joachim Fandrey, Eric Vivier, Veronika Sexl, Christian Stockmann
Published 2017-11-01

HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity

by Hiroaki Semba, Norihiko Takeda, Takayuki Isagawa, Yuki Sugiura, Kurara Honda, Masaki Wake, Hidenobu Miyazawa, Yoshifumi Yamaguchi, Masayuki Miura, Dana M. R. Jenkins, Hyunsung Choi, Jung-whan Kim, Masataka Asagiri, Andrew S. Cowburn, Hajime Abe, Katsura Soma, Katsuhiro Koyama, Manami Katoh, Keimon Sayama, Nobuhito Goda, Randall S. Johnson, Ichiro Manabe, Ryozo Nagai, Issei Komuro
Published 2016-05-01

Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M

by Hajime Abe, Norihiko Takeda, Takayuki Isagawa, Hiroaki Semba, Satoshi Nishimura, Masaki Suimye Morioka, Yu Nakagama, Tatsuyuki Sato, Katsura Soma, Katsuhiro Koyama, Masaki Wake, Manami Katoh, Masataka Asagiri, Michael L. Neugent, Jung-whan Kim, Christian Stockmann, Tomo Yonezawa, Ryo Inuzuka, Yasushi Hirota, Koji Maemura, Takeshi Yamashita, Kinya Otsu, Ichiro Manabe, Ryozo Nagai, Issei Komuro
Published 2019-06-01