Establishment of Novel Protein Interaction Assays between Sin3 and REST Using Surface Plasmon Resonance and Time-Resolved Fluorescence Energy Transfer

by Masamitsu Harada, Jun Nagai, Riho Kurata, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Published 2021-02-01

Establishment of Novel High-Standard Chemiluminescent Assay for NTPase in Two Protozoans and Its High-Throughput Screening

by Masamitsu Harada, Jun Nagai, Riho Kurata, Kenji Shimizu, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Jun Ishihara, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Published 2020-03-01

Novel Reporter System Monitoring IL-18 Specific Signaling Can Be Applied to High-Throughput Screening

by Riho Kurata, Kenji Shimizu, Xiaofeng Cui, Masamitsu Harada, Takayuki Isagawa, Hiroaki Semba, Jun Ishihara, Koji Yamada, Jun Nagai, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Published 2020-01-01

Comparison of risk models for mortality and cardiovascular events between machine learning and conventional logistic regression analysis.

by Shinya Suzuki, Takeshi Yamashita, Tsuyoshi Sakama, Takuto Arita, Naoharu Yagi, Takayuki Otsuka, Hiroaki Semba, Hiroto Kano, Shunsuke Matsuno, Yuko Kato, Tokuhisa Uejima, Yuji Oikawa, Minoru Matsuhama, Junji Yajima
Published 2019-01-01

Identifying risk patterns in older adults with atrial fibrillation by hierarchical cluster analysis: A retrospective approach based on the risk probability for clinical events

by Shinya Suzuki, Takeshi Yamashita, Takayuki Otsuka, Takuto Arita, Naoharu Yagi, Mikio Kishi, Hiroaki Semba, Hiroto Kano, Shunsuke Matsuno, Yuko Kato, Tokuhisa Uejima, Yuji Oikawa, Minoru Matsuhama, Mitsuru Iida, Tatsuya Inoue, Junji Yajima
Published 2021-12-01

Relationship between resting 12-lead electrocardiogram and all-cause death in patients without structural heart disease: Shinken Database analysis

by Naomi Hirota, Shinya Suzuki, Takuto Arita, Naoharu Yagi, Takayuki Otsuka, Mikio Kishi, Hiroaki Semba, Hiroto Kano, Shunsuke Matsuno, Yuko Kato, Tokuhisa Uejima, Yuji Oikawa, Minoru Matsuhama, Mitsuru Iida, Tatsuya Inoue, Junji Yajima, Takeshi Yamashita
Published 2021-02-01

HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity

by Hiroaki Semba, Norihiko Takeda, Takayuki Isagawa, Yuki Sugiura, Kurara Honda, Masaki Wake, Hidenobu Miyazawa, Yoshifumi Yamaguchi, Masayuki Miura, Dana M. R. Jenkins, Hyunsung Choi, Jung-whan Kim, Masataka Asagiri, Andrew S. Cowburn, Hajime Abe, Katsura Soma, Katsuhiro Koyama, Manami Katoh, Keimon Sayama, Nobuhito Goda, Randall S. Johnson, Ichiro Manabe, Ryozo Nagai, Issei Komuro
Published 2016-05-01

Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M

by Hajime Abe, Norihiko Takeda, Takayuki Isagawa, Hiroaki Semba, Satoshi Nishimura, Masaki Suimye Morioka, Yu Nakagama, Tatsuyuki Sato, Katsura Soma, Katsuhiro Koyama, Masaki Wake, Manami Katoh, Masataka Asagiri, Michael L. Neugent, Jung-whan Kim, Christian Stockmann, Tomo Yonezawa, Ryo Inuzuka, Yasushi Hirota, Koji Maemura, Takeshi Yamashita, Kinya Otsu, Ichiro Manabe, Ryozo Nagai, Issei Komuro
Published 2019-06-01