Extended Bloch–McConnell equations for mechanistic analysis of hyperpolarized ¹³C magnetic resonance experiments on enzyme systems

by T. R. Eykyn, S. J. Elliott, S. J. Elliott, P. W. Kuchel
Published 2021-06-01

Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells

by Christopher H. Switzer, Sebastian Guttzeit, Thomas R. Eykyn, Philip Eaton
Published 2021-11-01

Age-Dependent Decline in Cardiac Function in Guanidinoacetate-N-Methyltransferase Knockout Mice

by Dunja Aksentijević, Sevasti Zervou, Thomas R. Eykyn, Debra J. McAndrew, Julie Wallis, Jurgen E. Schneider, Stefan Neubauer, Craig A. Lygate
Published 2020-01-01

Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1

by Maia Kavanagh Williamson, Naomi Coombes, Florian Juszczak, Marios Athanasopoulos, Mariam B. Khan, Thomas R. Eykyn, Ushani Srenathan, Leonie S. Taams, Julianna Dias Zeidler, Andrea T. Da Poian, Hendrik Huthoff
Published 2018-03-01

Assessment of hepatic fatty acids during non-alcoholic steatohepatitis progression using magnetic resonance spectroscopy

by Aline Xavier, Flavia Zacconi, Fabián Santana-Romo, Thomas R. Eykyn, Begoña Lavin, Alkystis Phinikaridou, René Botnar, Sergio Uribe, Juan Esteban Oyarzún, Daniel Cabrera, Marco Arrese, Marcelo E. Andia
Published 2021-11-01

Lactate and choline metabolites detected in vitro by nuclear magnetic resonance spectroscopy are potential metabolic biomarkers for PI3K inhibition in pediatric glioblastoma.

by Nada M S Al-Saffar, Lynley V Marshall, L Elizabeth Jackson, Geetha Balarajah, Thomas R Eykyn, Alice Agliano, Paul A Clarke, Chris Jones, Paul Workman, Andrew D J Pearson, Martin O Leach
Published 2014-01-01

Intracellular sodium elevation reprograms cardiac metabolism

by Dunja Aksentijević, Anja Karlstaedt, Marina V. Basalay, Brett A. O’Brien, David Sanchez-Tatay, Seda Eminaga, Alpesh Thakker, Daniel A. Tennant, William Fuller, Thomas R. Eykyn, Heinrich Taegtmeyer, Michael J. Shattock
Published 2020-08-01

Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies.

by Gigin Lin, Gabriela Andrejeva, Anne-Christine Wong Te Fong, Deborah K Hill, Matthew R Orton, Harry G Parkes, Dow-Mu Koh, Simon P Robinson, Martin O Leach, Thomas R Eykyn, Yuen-Li Chung
Published 2014-01-01

Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data.

by Deborah K Hill, Matthew R Orton, Erika Mariotti, Jessica K R Boult, Rafal Panek, Maysam Jafar, Harold G Parkes, Yann Jamin, Maria Falck Miniotis, Nada M S Al-Saffar, Mounia Beloueche-Babari, Simon P Robinson, Martin O Leach, Yuen-Li Chung, Thomas R Eykyn
Published 2013-01-01

Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart

by Sevasti Zervou, Sevasti Zervou, Debra J. McAndrew, Debra J. McAndrew, Hannah J. Whittington, Hannah J. Whittington, Hannah A. Lake, Hannah A. Lake, Kyung Chan Park, Kyung Chan Park, Kyung Chan Park, Kuan Minn Cha, Kuan Minn Cha, Philip J. Ostrowski, Philip J. Ostrowski, Thomas R. Eykyn, Jürgen E. Schneider, Stefan Neubauer, Stefan Neubauer, Craig A. Lygate, Craig A. Lygate
Published 2021-03-01