A novel roadmap connecting the 1H-MRS total choline resonance to all hallmarks of cancer following targeted therapy

by Egidio Iorio, Franca Podo, Martin O. Leach, Jason Koutcher, Francis G. Blankenberg, Joseph F. Norfray
Published 2021-01-01

Wireless Accelerometer for MRI-Guided Interventional Procedures

by Martyn N.J. Paley, Araminta Ledger, Martin O. Leach, Craig Cummings, Raymond Hughes, Ali Akgun
Published 2013-12-01

Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System

by Victoria Sherwood, John Civale, Ian Rivens, David J. Collins, Martin O. Leach, Gail R. ter Haar
Published 2014-01-01

MRI texture feature repeatability and image acquisition factor robustness, a phantom study and in silico study

by Joshua Shur, Matthew Blackledge, James D’Arcy, David J. Collins, Maria Bali, Martin O’Leach, Dow-Mu Koh
Published 2021-01-01

Inter- and Intra-Observer Repeatability of Quantitative Whole-Body, Diffusion-Weighted Imaging (WBDWI) in Metastatic Bone Disease.

by Matthew D Blackledge, Nina Tunariu, Matthew R Orton, Anwar R Padhani, David J Collins, Martin O Leach, Dow-Mu Koh
Published 2016-01-01

Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibilit...

by Matthew D Blackledge, David J Collins, Nina Tunariu, Matthew R Orton, Anwar R Padhani, Martin O Leach, Dow-Mu Koh
Published 2014-01-01

Supervised Machine-Learning Enables Segmentation and Evaluation of Heterogeneous Post-treatment Changes in Multi-Parametric MRI of Soft-Tissue Sarcoma

by Matthew D. Blackledge, Jessica M. Winfield, Jessica M. Winfield, Aisha Miah, Aisha Miah, Dirk Strauss, Khin Thway, Khin Thway, Veronica A. Morgan, Veronica A. Morgan, David J. Collins, David J. Collins, Dow-Mu Koh, Dow-Mu Koh, Martin O. Leach, Martin O. Leach, Christina Messiou, Christina Messiou
Published 2019-10-01

Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging

by Anant Shah, Teresa Delgado-Goni, Teresa Casals Galobart, Slawomir Wantuch, Yann Jamin, Martin O. Leach, Simon P. Robinson, Jeffrey Bamber, Mounia Beloueche-Babari
Published 2017-08-01

Comparison of Dixon Sequences for Estimation of Percent Breast Fibroglandular Tissue.

by Araminta E W Ledger, Erica D Scurr, Julie Hughes, Alison Macdonald, Toni Wallace, Karen Thomas, Robin Wilson, Martin O Leach, Maria A Schmidt
Published 2016-01-01

Visualizing whole-body treatment response heterogeneity using multi-parametric magnetic resonance imaging

by Matthew D Blackledge, Mihaela Rata, Nina Tunariu, Dow-Mu Koh, Angela George, Andrea Zivi, David Lorente, Gerhardt Attard, Johann S de Bono, Martin O Leach, David J Collins
Published 2016-12-01

Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of a Novel Histone Deacetylase Inhibitor, LAQ824, in Human Colon Carcinoma Cells and Xenografts

by Yuen-Li Chung, Helen Troy, Rebecca Kristeleit, Wynne Aherne, L. Elizabeth Jackson, Peter Atadja, John R. Griffiths, Ian R. Judson, Paul Workman, Martin O. Leach, Mounia Beloueche-Babari
Published 2008-04-01

Characterizing Heterogeneity within Head and Neck Lesions Using Cluster Analysis of Multi-Parametric MRI Data.

by Marco Borri, Maria A Schmidt, Ceri Powell, Dow-Mu Koh, Angela M Riddell, Mike Partridge, Shreerang A Bhide, Christopher M Nutting, Kevin J Harrington, Katie L Newbold, Martin O Leach
Published 2015-01-01

In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells.

by Nada M S Al-Saffar, Alice Agliano, Lynley V Marshall, L Elizabeth Jackson, Geetha Balarajah, Jasmin Sidhu, Paul A Clarke, Chris Jones, Paul Workman, Andrew D J Pearson, Martin O Leach
Published 2017-01-01

Microstructure Characterization of Bone Metastases from Prostate Cancer with Diffusion MRI: Preliminary Findings

by Colleen Bailey, Colleen Bailey, David J. Collins, Nina Tunariu, Matthew R. Orton, Veronica A. Morgan, Thorsten Feiweier, David J. Hawkes, Martin O. Leach, Daniel C. Alexander, Daniel C. Alexander, Eleftheria Panagiotaki
Published 2018-02-01

Lactate and choline metabolites detected in vitro by nuclear magnetic resonance spectroscopy are potential metabolic biomarkers for PI3K inhibition in pediatric glioblastoma.

by Nada M S Al-Saffar, Lynley V Marshall, L Elizabeth Jackson, Geetha Balarajah, Thomas R Eykyn, Alice Agliano, Paul A Clarke, Chris Jones, Paul Workman, Andrew D J Pearson, Martin O Leach
Published 2014-01-01

Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies.

by Gigin Lin, Gabriela Andrejeva, Anne-Christine Wong Te Fong, Deborah K Hill, Matthew R Orton, Harry G Parkes, Dow-Mu Koh, Simon P Robinson, Martin O Leach, Thomas R Eykyn, Yuen-Li Chung
Published 2014-01-01

Noise-Corrected, Exponentially Weighted, Diffusion-Weighted MRI (niceDWI) Improves Image Signal Uniformity in Whole-Body Imaging of Metastatic Prostate Cancer

by Matthew D. Blackledge, Nina Tunariu, Nina Tunariu, Fabio Zugni, Fabio Zugni, Richard Holbrey, Matthew R. Orton, Ana Ribeiro, Julie C. Hughes, Erica D. Scurr, David J. Collins, Martin O. Leach, Dow-Mu Koh, Dow-Mu Koh
Published 2020-05-01

Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

by John Kurhanewicz, Daniel B. Vigneron, Kevin Brindle, Eduard Y. Chekmenev, Arnaud Comment, Charles H. Cunningham, Ralph J. DeBerardinis, Gary G. Green, Martin O. Leach, Sunder S. Rajan, Rahim R. Rizi, Brian D. Ross, Warren S. Warren, Craig R. Malloy
Published 2011-02-01

Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma

by Lauren C. J. Baker, Arti Sikka, Jonathan M. Price, Jessica K. R. Boult, Elise Y. Lepicard, Gary Box, Yann Jamin, Terry J. Spinks, Gabriela Kramer-Marek, Martin O. Leach, Suzanne A. Eccles, Carol Box, Carol Box, Simon P. Robinson
Published 2018-07-01

Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data.

by Deborah K Hill, Matthew R Orton, Erika Mariotti, Jessica K R Boult, Rafal Panek, Maysam Jafar, Harold G Parkes, Yann Jamin, Maria Falck Miniotis, Nada M S Al-Saffar, Mounia Beloueche-Babari, Simon P Robinson, Martin O Leach, Yuen-Li Chung, Thomas R Eykyn
Published 2013-01-01