So many ways to naturally kill a cancer cell

by Timothy J. Mitchison
Published 2021-07-01

Unsupervised identification of disease states from high‐dimensional physiological and histopathological profiles

by Kenichi Shimada, Timothy J Mitchison
Published 2019-02-01

Physical basis of large microtubule aster growth

by Keisuke Ishihara, Kirill S Korolev, Timothy J Mitchison
Published 2016-11-01

Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug?

by T. J. Mitchison, J. Pineda, J. Shi, S. Florian
Published 2017-01-01

Vascular disrupting agent drug classes differ in effects on the cytoskeleton.

by Sujeong Kim, Leonid Peshkin, Timothy J Mitchison
Published 2012-01-01

Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues.

by Ivana Gasic, Sarah A Boswell, Timothy J Mitchison
Published 2019-04-01

Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest.

by Hsiao-Chun Huang, Timothy J Mitchison, Jue Shi
Published 2010-12-01

shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data

by Kenichi Shimada, John A Bachman, Jeremy L Muhlich, Timothy J Mitchison
Published 2021-02-01

Basal Activity of a PARP1-NuA4 Complex Varies Dramatically across Cancer Cell Lines

by Kristin A. Krukenberg, Ruomu Jiang, Judith A. Steen, Timothy J. Mitchison
Published 2014-09-01

Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm

by James F Pelletier, Christine M Field, Sebastian Fürthauer, Matthew Sonnett, Timothy J Mitchison
Published 2020-12-01

Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets.

by Ulrike S Eggert, Amy A Kiger, Constance Richter, Zachary E Perlman, Norbert Perrimon, Timothy J Mitchison, Christine M Field
Published 2004-12-01

Tubulin Resists Degradation by Cereblon-Recruiting PROTACs

by Ivana Gasic, Brian J. Groendyke, Radosław P. Nowak, J. Christine Yuan, Joann Kalabathula, Eric S. Fischer, Nathanael S. Gray, Timothy J. Mitchison
Published 2020-04-01

An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor.

by Melody Tsui, Tiao Xie, James D Orth, Anne E Carpenter, Stewart Rudnicki, Suejong Kim, Caroline E Shamu, Timothy J Mitchison
Published 2009-10-01

In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells

by Gaurav Luthria, Ran Li, Stephanie Wang, Mark Prytyskach, Rainer H. Kohler, Douglas A. Lauffenburger, Timothy J. Mitchison, Ralph Weissleder, Miles A. Miller
Published 2020-07-01

27 T ultra-high static magnetic field changes orientation and morphology of mitotic spindles in human cells

by Lei Zhang, Yubin Hou, Zhiyuan Li, Xinmiao Ji, Ze Wang, Huizhen Wang, Xiaofei Tian, Fazhi Yu, Zhenye Yang, Li Pi, Timothy J Mitchison, Qingyou Lu, Xin Zhang
Published 2017-02-01

Correction: 27 T ultra-high static magnetic field changes orientation and morphology of mitotic spindles in human cells

by Lei Zhang, Yubin Hou, Zhiyuan Li, Xinmiao Ji, Ze Wang, Huizhen Wang, Xiaofei Tian, Fazhi Yu, Zhenye Yang, Li Pi, Timothy J Mitchison, Qingyou Lu, Xin Zhang
Published 2017-05-01

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

by M Catarina Silva, Fleur M Ferguson, Quan Cai, Katherine A Donovan, Ghata Nandi, Debasis Patnaik, Tinghu Zhang, Hai-Tsang Huang, Diane E Lucente, Bradford C Dickerson, Timothy J Mitchison, Eric S Fischer, Nathanael S Gray, Stephen J Haggarty
Published 2019-03-01

Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

by Yubao Wang, Young-Mi Li, Lukas Baitsch, Alan Huang, Yi Xiang, Haoxuan Tong, Ana Lako, Thanh Von, Christine Choi, Elgene Lim, Junxia Min, Li Li, Frank Stegmeier, Robert Schlegel, Michael J Eck, Nathanael S Gray, Timothy J Mitchison, Jean J Zhao
Published 2018-03-01

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

by Yubao Wang, Young-Mi Lee, Lukas Baitsch, Alan Huang, Yi Xiang, Haoxuan Tong, Ana Lako, Thanh Von, Christine Choi, Elgene Lim, Junxia Min, Li Li, Frank Stegmeier, Robert Schlegel, Michael J Eck, Nathanael S Gray, Timothy J Mitchison, Jean J Zhao
Published 2014-05-01

A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine

by Hyun Jung Jun, Vicky A. Appleman, Hua-Jun Wu, Christopher M. Rose, Javier J. Pineda, Alan T. Yeo, Bethany Delcuze, Charlotte Lee, Aron Gyuris, Haihao Zhu, Steve Woolfenden, Agnieszka Bronisz, Ichiro Nakano, Ennio A. Chiocca, Roderick T. Bronson, Keith L. Ligon, Jann N. Sarkaria, Steve P. Gygi, Franziska Michor, Timothy J. Mitchison, Al Charest
Published 2018-08-01