Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines

by Alan T. Yeo, Spandan Chennamadhavuni, Adrian Whitty, John A. Porco, Thomas D. Gilmore
Published 2015-04-01

CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein.

by Milad Babaei, Yuekun Liu, Shelly M Wuerzberger-Davis, Ethan Z McCaslin, Christopher J DiRusso, Alan T Yeo, Larisa Kagermazova, Shigeki Miyamoto, Thomas D Gilmore
Published 2019-01-01

A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine

by Hyun Jung Jun, Vicky A. Appleman, Hua-Jun Wu, Christopher M. Rose, Javier J. Pineda, Alan T. Yeo, Bethany Delcuze, Charlotte Lee, Aron Gyuris, Haihao Zhu, Steve Woolfenden, Agnieszka Bronisz, Ichiro Nakano, Ennio A. Chiocca, Roderick T. Bronson, Keith L. Ligon, Jann N. Sarkaria, Steve P. Gygi, Franziska Michor, Timothy J. Mitchison, Al Charest
Published 2018-08-01