Targeted Serum Metabolite Profiling Identifies Metabolic Signatures in Patients with Alzheimer's Disease, Normal Pressure Hydrocephalus and Brain Tumor

by Matej Orešič, Matej Orešič, Gabriella Anderson, Ismo Mattila, Manoucher Manoucheri, Hilkka Soininen, Hilkka Soininen, Tuulia Hyötyläinen, Tuulia Hyötyläinen, Cherlynn Basignani
Published 2018-01-01

Serum untargeted lipidomic profiling reveals dysfunction of phospholipid metabolism in subclinical coronary artery disease

by Djekic D, Pinto R, Repsilber D, Hyotylainen T, Henein M
Published 2019-05-01

Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2

by Alexandra Robciuc, Tuulia Hyötyläinen, Matti Jauhiainen, Juha M. Holopainen
Published 2012-11-01

Metabolic Signatures of the Exposome—Quantifying the Impact of Exposure to Environmental Chemicals on Human Health

by Matej Orešič, Aidan McGlinchey, Craig E. Wheelock, Tuulia Hyötyläinen
Published 2020-11-01

The gut microbiota modulates glycaemic control and serum metabolite profiles in non-obese diabetic mice.

by Thomas U Greiner, Tuulia Hyötyläinen, Mikael Knip, Fredrik Bäckhed, Matej Orešič
Published 2014-01-01

Effects of a Lacto-Ovo-Vegetarian Diet on the Plasma Lipidome and Its Association with Atherosclerotic Burden in Patients with Coronary Artery Disease—A Randomized, Open-Label, Cro...

by Demir Djekic, Lin Shi, Fredrik Calais, Frida Carlsson, Rikard Landberg, Tuulia Hyötyläinen, Ole Frøbert
Published 2020-11-01

Lipidomic Analyses Reveal Modulation of Lipid Metabolism by the PFAS Perfluoroundecanoic Acid (PFUnDA) in Non-Obese Diabetic Mice

by Tuulia Hyötyläinen, Johanna Bodin, Daniel Duberg, Hubert Dirven, Unni C. Nygaard, Matej Orešič, Matej Orešič
Published 2021-09-01

Linking Gut Microbiome and Lipid Metabolism: Moving beyond Associations

by Santosh Lamichhane, Partho Sen, Marina Amaral Alves, Henrique C. Ribeiro, Peppi Raunioniemi, Tuulia Hyötyläinen, Matej Orešič
Published 2021-01-01

Exposure to per- and polyfluoroalkyl substances associates with an altered lipid composition of breast milk

by Santosh Lamichhane, Heli Siljander, Daniel Duberg, Jarno Honkanen, Suvi M. Virtanen, Matej Orešič, Mikael Knip, Tuulia Hyötyläinen
Published 2021-12-01

Targeted Clinical Metabolite Profiling Platform for the Stratification of Diabetic Patients

by Linda Ahonen, Sirkku Jäntti, Tommi Suvitaival, Simone Theilade, Claudia Risz, Risto Kostiainen, Peter Rossing, Matej Orešič, Tuulia Hyötyläinen
Published 2019-09-01

Mondo/ChREBP-Mlx-regulated transcriptional network is essential for dietary sugar tolerance in Drosophila.

by Essi Havula, Mari Teesalu, Tuulia Hyötyläinen, Heini Seppälä, Kiran Hasygar, Petri Auvinen, Matej Orešič, Thomas Sandmann, Ville Hietakangas
Published 2013-04-01

Loss of <it>Drosophila</it> Mondo-Mlx reveals a model for exploring the genetic basis of dietary sugar tolerance

by Hyötyläinen Tuulia, Orešic Matej, Havula Essi, Teesalu Mari, Seppälä Heini, Hasygar Kiran, Auvinen Petri, Sandmann Thomas, Hietakangas Ville
Published 2012-06-01

Generation of a human induced pluripotent stem cell line (LL008 1.4) from a familial Alzheimer's disease patient carrying a double KM670/671NL (Swedish) mutation in APP gene

by Minna Oksanen, Ida Hyötyläinen, Jenni Voutilainen, Katja A. Puttonen, Riikka H. Hämäläinen, Caroline Graff, Šárka Lehtonen, Jari Koistinaho
Published 2018-08-01

Metabolomics Profiling As a Diagnostic Tool in Severe Traumatic Brain Injury

by Jussi P. Posti, Jussi P. Posti, Jussi P. Posti, Alex M. Dickens, Matej Orešič, Tuulia Hyötyläinen, Olli Tenovuo, Olli Tenovuo
Published 2017-08-01

Integrative Analysis of Circulating Metabolite Profiles and Magnetic Resonance Imaging Metrics in Patients with Traumatic Brain Injury

by Ilias Thomas, Alex M. Dickens, Jussi P. Posti, Mehrbod Mohammadian, Christian Ledig, Riikka S. K. Takala, Tuulia Hyötyläinen, Olli Tenovuo, Matej Orešič
Published 2020-02-01

Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease

by Tuulia Hyötyläinen, Livnat Jerby, Elina M. Petäjä, Ismo Mattila, Sirkku Jäntti, Petri Auvinen, Amalia Gastaldelli, Hannele Yki-Järvinen, Eytan Ruppin, Matej Orešič
Published 2016-02-01

Spatial distribution of glycerophospholipids in the ocular lens.

by Jaroslav Pól, Veronika Vidová, Tuulia Hyötyläinen, Michael Volný, Petr Novák, Martin Strohalm, Risto Kostiainen, Vladimír Havlíček, Susanne K Wiedmer, Juha M Holopainen
Published 2011-04-01

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy.

by Benedicte Jørgenrud, Mikko Jalanko, Tiina Heliö, Pertti Jääskeläinen, Mika Laine, Mika Hilvo, Markku S Nieminen, Markku Laakso, Tuulia Hyötyläinen, Matej Orešič, Johanna Kuusisto
Published 2015-01-01

Cord-Blood Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes

by Santosh Lamichhane, Linda Ahonen, Thomas Sparholt Dyrlund, Alex M. Dickens, Heli Siljander, Heikki Hyöty, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Tuulia Hyötyläinen, Mikael Knip, Matej Oresic
Published 2019-01-01

Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects.

by Inger Ottestad, Sahar Hassani, Grethe I Borge, Achim Kohler, Gjermund Vogt, Tuulia Hyötyläinen, Matej Orešič, Kirsti W Brønner, Kirsten B Holven, Stine M Ulven, Mari C W Myhrstad
Published 2012-01-01