The expanding toolkit for structural biology: synchrotrons, X-ray lasers and cryoEM

by Stephen P. Muench, Svetlana V. Antonyuk, S. Samar Hasnain
Published 2019-03-01

Sub-atomic resolution X-ray crystallography and neutron crystallography: promise, challenges and potential

by Matthew P. Blakeley, Samar S. Hasnain, Svetlana V. Antonyuk
Published 2015-07-01

Crystal Structure of the Japanese Encephalitis Virus Capsid Protein

by Thanalai Poonsiri, Gareth S. A. Wright, Tom Solomon, Svetlana V. Antonyuk
Published 2019-07-01

Structural evidence for a copper-bound carbonate intermediate in the peroxidase and dismutase activities of superoxide dismutase.

by Richard W Strange, Michael A Hough, Svetlana V Antonyuk, S Samar Hasnain
Published 2012-01-01

Identification of a tyrosine switch in copper-haem nitrite reductases

by Jianshu Dong, Daisuke Sasaki, Robert R. Eady, Svetlana V. Antonyuk, S. Samar Hasnain
Published 2018-07-01

Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS.

by Fernanda A Sala, Gareth S A Wright, Svetlana V Antonyuk, Richard C Garratt, S Samar Hasnain
Published 2019-02-01

Structures of substrate- and product-bound forms of a multi-domain copper nitrite reductase shed light on the role of domain tethering in protein complexes

by Daisuke Sasaki, Tatiana F. Watanabe, Robert R. Eady, Richard C. Garratt, Svetlana V. Antonyuk, S. Samar Hasnain
Published 2020-05-01

Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal

by Sam Horrell, Svetlana V. Antonyuk, Robert R. Eady, S. Samar Hasnain, Michael A. Hough, Richard W. Strange
Published 2016-07-01

Purification and Structural Characterization of Aggregation-Prone Human TDP-43 Involved in Neurodegenerative Diseases

by Gareth S.A. Wright, Tatiana F. Watanabe, Kangsa Amporndanai, Steven S. Plotkin, Neil R. Cashman, Svetlana V. Antonyuk, S. Samar Hasnain
Published 2020-06-01

Structure and function study of the complex that synthesizes S-adenosylmethionine

by Ben Murray, Svetlana V. Antonyuk, Alberto Marina, Sebastiaan M. Van Liempd, Shelly C. Lu, Jose M. Mato, S. Samar Hasnain, Adriana L. Rojas
Published 2014-07-01

An unprecedented dioxygen species revealed by serial femtosecond rotation crystallography in copper nitrite reductase

by Thomas P. Halsted, Keitaro Yamashita, Kunio Hirata, Hideo Ago, Go Ueno, Takehiko Tosha, Robert R. Eady, Svetlana V. Antonyuk, Masaki Yamamoto, S. Samar Hasnain
Published 2018-01-01

The active form of quinol-dependent nitric oxide reductase from Neisseria meningitidis is a dimer

by M. Arif M. Jamali, Chai C. Gopalasingam, Rachel M. Johnson, Takehiko Tosha, Kazumasa Muramoto, Stephen P. Muench, Svetlana V. Antonyuk, Yoshitsugu Shiro, Samar S. Hasnain
Published 2020-05-01

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery

by Kangsa Amporndanai, Rachel M. Johnson, Paul M. O'Neill, Colin W. G. Fishwick, Alexander H. Jamson, Shaun Rawson, Stephen P. Muench, S. Samar Hasnain, Svetlana V. Antonyuk
Published 2018-03-01

The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation

by Michael J. Capper, Gareth S. A. Wright, Letizia Barbieri, Enrico Luchinat, Eleonora Mercatelli, Luke McAlary, Justin J. Yerbury, Paul M. O’Neill, Svetlana V. Antonyuk, Lucia Banci, S. Samar Hasnain
Published 2018-04-01

Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography

by Thomas P. Halsted, Keitaro Yamashita, Chai C. Gopalasingam, Rajesh T. Shenoy, Kunio Hirata, Hideo Ago, Go Ueno, Matthew P. Blakeley, Robert R. Eady, Svetlana V. Antonyuk, Masaki Yamamoto, S. Samar Hasnain
Published 2019-07-01

Enzyme catalysis captured using multiple structures from one crystal at varying temperatures

by Sam Horrell, Demet Kekilli, Kakali Sen, Robin L. Owen, Florian S. N. Dworkowski, Svetlana V. Antonyuk, Thomas W. Keal, Chin W. Yong, Robert R. Eady, S. Samar Hasnain, Richard W. Strange, Michael A. Hough
Published 2018-05-01

Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites

by Martin J. McPhillie, Ying Zhou, Mark R. Hickman, James A. Gordon, Christopher R. Weber, Qigui Li, Patty J. Lee, Kangsa Amporndanai, Rachel M. Johnson, Heather Darby, Stuart Woods, Zhu-hong Li, Richard S. Priestley, Kurt D. Ristroph, Scott B. Biering, Kamal El Bissati, Seungmin Hwang, Farida Esaa Hakim, Sarah M. Dovgin, Joseph D. Lykins, Lucy Roberts, Kerrie Hargrave, Hua Cong, Anthony P. Sinai, Stephen P. Muench, Jitender P. Dubey, Robert K. Prud'homme, Hernan A. Lorenzi, Giancarlo A. Biagini, Silvia N. Moreno, Craig W. Roberts, Svetlana V. Antonyuk, Colin W. G. Fishwick, Rima McLeod, Rima McLeod
Published 2020-06-01