A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies

by Matthew A. Cottee, Steven Johnson, Jordan W. Raff, Susan M. Lea
Published 2017-03-01

Nonameric structures of the cytoplasmic domain of FlhA and SctV in the context of the full-length protein.

by Lucas Kuhlen, Steven Johnson, Jerry Cao, Justin C Deme, Susan M Lea
Published 2021-01-01

The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems

by Steven Johnson, Lucas Kuhlen, Justin C. Deme, Patrizia Abrusci, Susan M. Lea
Published 2019-06-01

Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59

by Steven Johnson, Nicholas J. Brooks, Richard A.G. Smith, Susan M. Lea, Doryen Bubeck
Published 2013-05-01

Functional analysis of the interdependence between DNA uptake sequence and its cognate ComP receptor during natural transformation in Neisseria species.

by Jamie-Lee Berry, Ana Cehovin, Melanie A McDowell, Susan M Lea, Vladimir Pelicic
Published 2013-01-01

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

by Matthew A Cottee, Nadine Muschalik, Steven Johnson, Joanna Leveson, Jordan W Raff, Susan M Lea
Published 2015-05-01

Different modes of variation for each BG lineage suggest different functions

by John Chattaway, R. Andrei Ramirez-Valdez, Paul E. Chappell, Joseph J. E. Caesar, Susan M. Lea, Jim Kaufman
Published 2016-01-01

Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex

by Yoel A. Klug, Justin C. Deme, Robin A. Corey, Mike F. Renne, Phillip J. Stansfeld, Susan M. Lea, Pedro Carvalho
Published 2021-10-01

Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein.

by Ilse Jongerius, Hayley Lavender, Lionel Tan, Nicola Ruivo, Rachel M Exley, Joseph J E Caesar, Susan M Lea, Steven Johnson, Christoph M Tang
Published 2013-01-01

The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion

by Lucas Kuhlen, Steven Johnson, Andreas Zeitler, Sandra Bäurle, Justin C. Deme, Joseph J.  E. Caesar, Rebecca Debo, Joseph Fisher, Samuel Wagner, Susan M. Lea
Published 2020-03-01

SIMPLE 3.0. Stream single-particle cryo-EM analysis in real time

by Joseph Caesar, Cyril F. Reboul, Chiara Machello, Simon Kiesewetter, Molly L. Tang, Justin C. Deme, Steven Johnson, Dominika Elmlund, Susan M. Lea, Hans Elmlund
Published 2020-01-01

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9

by Michael A. Hadders, Doryen Bubeck, Pietro Roversi, Svetlana Hakobyan, Federico Forneris, B. Paul Morgan, Michael K. Pangburn, Oscar Llorca, Susan M. Lea, Piet Gros
Published 2012-03-01

Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands

by Chandramouli R. Chillakuri, Devon Sheppard, Ma. Xenia G. Ilagan, Laurie R. Holt, Felicity Abbott, Shaoyan Liang, Raphael Kopan, Penny A. Handford, Susan M. Lea
Published 2013-11-01

Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly

by Matthew A Cottee, Nadine Muschalik, Yao Liang Wong, Christopher M Johnson, Steven Johnson, Antonina Andreeva, Karen Oegema, Susan M Lea, Jordan W Raff, Mark van Breugel
Published 2013-09-01

Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility

by Joseph JE Caesar, Hayley Lavender, Philip N Ward, Rachel M Exley, Jack Eaton, Emily Chittock, Talat H Malik, Elena Goiecoechea De Jorge, Matthew C Pickering, Christoph M Tang, Susan M Lea
Published 2014-12-01

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

by Paul E Chappell, El Kahina Meziane, Michael Harrison, Łukasz Magiera, Clemens Hermann, Laura Mears, Antoni G Wrobel, Charlotte Durant, Lise Lotte Nielsen, Søren Buus, Nicola Ternette, William Mwangi, Colin Butter, Venugopal Nair, Trudy Ahyee, Richard Duggleby, Alejandro Madrigal, Pietro Roversi, Susan M Lea, Jim Kaufman
Published 2015-04-01

Correction: Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

by Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J. Harding, Xilian Bai, Rachel M. Exley, Philip N. Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C. Pickering, Susan M. Lea, Christoph M. Tang
Published 2013-01-01

Correction: Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules.

by Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J. Harding, Xilian Bai, Rachel M. Exley, Philip N. Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C. Pickering, Susan M. Lea, Christoph M. Tang
Published 2013-01-01

Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules.

by Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J Harding, Xilian Bai, Rachel M Exley, Philip N Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C Pickering, Susan M Lea, Christoph M Tang
Published 2012-01-01