A Paradox in Bacterial Pathogenesis: Activation of the Local Macrophage Inflammasome Is Required for Virulence of <i>Streptococcus uberis</i>

by Nathan Archer, Sharon A. Egan, Tracey J. Coffey, Richard D. Emes, M. Filippa Addis, Philip N. Ward, Adam M. Blanchard, James A. Leigh
Published 2020-11-01

The molecular basis of regulation of bacterial capsule assembly by Wzc

by Yun Yang, Jiwei Liu, Bradley R. Clarke, Laura Seidel, Jani R. Bolla, Philip N. Ward, Peijun Zhang, Carol V. Robinson, Chris Whitfield, James H. Naismith
Published 2021-07-01

Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility

by Joseph JE Caesar, Hayley Lavender, Philip N Ward, Rachel M Exley, Jack Eaton, Emily Chittock, Talat H Malik, Elena Goiecoechea De Jorge, Matthew C Pickering, Christoph M Tang, Susan M Lea
Published 2014-12-01

Correction: Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

by Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J. Harding, Xilian Bai, Rachel M. Exley, Philip N. Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C. Pickering, Susan M. Lea, Christoph M. Tang
Published 2013-01-01

Correction: Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules.

by Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J. Harding, Xilian Bai, Rachel M. Exley, Philip N. Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C. Pickering, Susan M. Lea, Christoph M. Tang
Published 2013-01-01

Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules.

by Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J Harding, Xilian Bai, Rachel M Exley, Philip N Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C Pickering, Susan M Lea, Christoph M Tang
Published 2012-01-01

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

by Jiandong Huo, Halina Mikolajek, Audrey Le Bas, Jordan J. Clark, Parul Sharma, Anja Kipar, Joshua Dormon, Chelsea Norman, Miriam Weckener, Daniel K. Clare, Peter J. Harrison, Julia A. Tree, Karen R. Buttigieg, Francisco J. Salguero, Robert Watson, Daniel Knott, Oliver Carnell, Didier Ngabo, Michael J. Elmore, Susan Fotheringham, Adam Harding, Lucile Moynié, Philip N. Ward, Maud Dumoux, Tessa Prince, Yper Hall, Julian A. Hiscox, Andrew Owen, William James, Miles W. Carroll, James P. Stewart, James H. Naismith, Raymond J. Owens
Published 2021-09-01

Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis.

by Matthew T G Holden, Heidi Hauser, Mandy Sanders, Thi Hoa Ngo, Inna Cherevach, Ann Cronin, Ian Goodhead, Karen Mungall, Michael A Quail, Claire Price, Ester Rabbinowitsch, Sarah Sharp, Nicholas J Croucher, Tran Bich Chieu, Nguyen Thi Hoang Mai, To Song Diep, Nguyen Tran Chinh, Michael Kehoe, James A Leigh, Philip N Ward, Christopher G Dowson, Adrian M Whatmore, Neil Chanter, Pernille Iversen, Marcelo Gottschalk, Josh D Slater, Hilde E Smith, Brian G Spratt, Jianguo Xu, Changyun Ye, Stephen Bentley, Barclay G Barrell, Constance Schultsz, Duncan J Maskell, Julian Parkhill
Published 2009-07-01