PD-L1 Multiplex and Quantitative Image Analysis for Molecular Diagnostics

by Fatima Abdullahi Sidi, Victoria Bingham, Stephanie G. Craig, Stephen McQuaid, Jacqueline James, Matthew P. Humphries, Manuel Salto-Tellez
Published 2021-12-01

Improving the Diagnostic Accuracy of the PD-L1 Test with Image Analysis and Multiplex Hybridization

by Matthew P. Humphries, Victoria Bingham, Fatima Abdullahi Sidi, Stephanie G. Craig, Stephen McQuaid, Jacqueline James, Manuel Salto-Tellez
Published 2020-04-01

A Means of Assessing Deep Learning-Based Detection of ICOS Protein Expression in Colon Cancer

by Md Mostafa Kamal Sarker, Yasmine Makhlouf, Stephanie G. Craig, Matthew P. Humphries, Maurice Loughrey, Jacqueline A. James, Manuel Salto-Tellez, Paul O’Reilly, Perry Maxwell
Published 2021-07-01

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

by James S. Smith, Katrina M. Lappin, Stephanie G. Craig, Fabio G. Liberante, Clare M. Crean, Simon S. McDade, Alexander Thompson, Ken I. Mills, Kienan I. Savage
Published 2020-09-01

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

by Ross J Porter, Graeme I Murray, Abdo Alnabulsi, Matthew P Humphries, Jacqueline A James, Manuel Salto‐Tellez, Stephanie G Craig, Ji M Wang, Teizo Yoshimura, Mairi H McLean
Published 2021-09-01

The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation

by Matthew P. Humphries, Stephanie G. Craig, Rafal Kacprzyk, Natalie C. Fisher, Victoria Bingham, Stephen McQuaid, Graeme I. Murray, Damian McManus, Richard C. Turkington, Jacqueline James, Manuel Salto-Tellez
Published 2020-06-01

HistoClean: Open-source software for histological image pre-processing and augmentation to improve development of robust convolutional neural networks

by Kris D. McCombe, Stephanie G. Craig, Amélie Viratham Pulsawatdi, Javier I. Quezada-Marín, Matthew Hagan, Simon Rajendran, Matthew P. Humphries, Victoria Bingham, Manuel Salto-Tellez, Richard Gault, Jacqueline A. James
Published 2021-01-01

A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment

by Amélie Viratham Pulsawatdi, Stephanie G. Craig, Victoria Bingham, Kris McCombe, Matthew P. Humphries, Seedevi Senevirathne, Susan D. Richman, Phil Quirke, Leticia Campo, Enric Domingo, Timothy S. Maughan, Jacqueline A. James, Manuel Salto‐Tellez
Published 2020-10-01