Use of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures.

by Luca G Mariotti, Giacomo Pirovano, Kienan I Savage, Mihaela Ghita, Andrea Ottolenghi, Kevin M Prise, Giuseppe Schettino
Published 2013-01-01

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

by James S. Smith, Katrina M. Lappin, Stephanie G. Craig, Fabio G. Liberante, Clare M. Crean, Simon S. McDade, Alexander Thompson, Ken I. Mills, Kienan I. Savage
Published 2020-09-01

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

by Alkmini Kalousi, Anne-Sophie Hoffbeck, Platonas N. Selemenakis, Jordan Pinder, Kienan I. Savage, Kum Kum Khanna, Laurent Brino, Graham Dellaire, Vassilis G. Gorgoulis, Evi Soutoglou
Published 2015-04-01

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

by Amila Suraweera, Neha S. Gandhi, Sam Beard, Joshua T. Burgess, Laura V. Croft, Emma Bolderson, Ali Naqi, Nicholas W. Ashton, Mark N. Adams, Kienan I. Savage, Shu-Dong Zhang, Kenneth J. O’Byrne, Derek J. Richard
Published 2021-04-01

Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers

by Alan D McCrorie, Susannah Ashfield, Aislinn Begley, Colin Mcilmunn, Patrick J Morrison, Clinton Boyd, Bryony Eccles, Stephanie Greville‐Heygate, Ellen R Copson, Ramsey I Cutress, Diana M Eccles, Kienan I Savage, Stuart A McIntosh
Published 2020-04-01