Proteolytic α-Synuclein Cleavage in Health and Disease

by Alexandra Bluhm, Sarah Schrempel, Stephan von Hörsten, Anja Schulze, Steffen Roßner
Published 2021-05-01

Formation of HERV-K and HERV-Fc1 Envelope Family Members is Suppressed on Transcriptional and Translational Level

by Victoria Gröger, Lisa Wieland, Marcel Naumann, Ann-Christin Meinecke, Beate Meinhardt, Steffen Rossner, Christian Ihling, Alexander Emmer, Martin S. Staege, Holger Cynis
Published 2020-10-01

Cell Type-Specific Human APP Transgene Expression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer’s Disease

by Corinna Höfling, Emira Shehabi, Peer-Hendrik Kuhn, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Maike Hartlage-Rübsamen, Steffen Roßner
Published 2019-02-01

Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheime...

by Maike Hartlage-Rübsamen, Veronika Ratz, Ulrike Zeitschel, Lukas Finzel, Lisa Machner, Janett Köppen, Anja Schulze, Hans-Ulrich Demuth, Stephan von Hörsten, Corinna Höfling, Steffen Roßner
Published 2019-05-01

Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation

by Maike Hartlage-Rübsamen, Alexandra Bluhm, Anke Piechotta, Miriam Linnert, Jens-Ulrich Rahfeld, Hans-Ulrich Demuth, Inge Lues, Peer-Hendrik Kuhn, Stefan F. Lichtenthaler, Steffen Roßner, Corinna Höfling
Published 2018-04-01

A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Leprdb/db mice

by Claudia Berger, Henrike O. Heyne, Tina Heiland, Sebastian Dommel, Corinna Höfling, Esther Guiu-Jurado, Jana Lorenz, Steffen Roßner, Michael Dannemann, Janet Kelso, Peter Kovacs, Matthias Blüher, Nora Klöting
Published 2021-01-01

Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro

by Janett Köppen, Anja Schulze, Lisa Machner, Michael Wermann, Rico Eichentopf, Max Guthardt, Angelika Hähnel, Jessica Klehm, Marie-Christin Kriegeskorte, Maike Hartlage-Rübsamen, Markus Morawski, Stephan von Hörsten, Hans-Ulrich Demuth, Steffen Roßner, Stephan Schilling
Published 2020-01-01

Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology

by Kathrin Gnoth, Anke Piechotta, Martin Kleinschmidt, Sandra Konrath, Mathias Schenk, Nadine Taudte, Daniel Ramsbeck, Vera Rieckmann, Stefanie Geissler, Rico Eichentopf, Susan Barendrecht, Maike Hartlage-Rübsamen, Hans-Ulrich Demuth, Steffen Roßner, Holger Cynis, Jens-Ulrich Rahfeld, Stephan Schilling
Published 2020-11-01

QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain

by Sharon C. Yates, Nicolaas E. Groeneboom, Christopher Coello, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Peer-Hendrik Kuhn, Hans-Ulrich Demuth, Maike Hartlage-Rübsamen, Steffen Roßner, Trygve Leergaard, Anna Kreshuk, Maja A. Puchades, Jan G. Bjaalie
Published 2019-12-01