Unexpected Impact of a Hepatitis C Virus Inhibitor on 17β-Estradiol Signaling in Breast Cancer

by Stefania Bartoloni, Stefano Leone, Filippo Acconcia
Published 2020-05-01

Oxidative Stress Induces Telomere Dysfunction and Senescence by Replication Fork Arrest

by Elisa Coluzzi, Stefano Leone, Antonella Sgura
Published 2019-01-01

A New Anti-Estrogen Discovery Platform Identifies FDA-Approved Imidazole Anti-Fungal Drugs as Bioactive Compounds against ERα Expressing Breast Cancer Cells

by Manuela Cipolletti, Stefania Bartoloni, Claudia Busonero, Martina Parente, Stefano Leone, Filippo Acconcia
Published 2021-03-01

Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells.

by Elisa Coluzzi, Monica Colamartino, Renata Cozzi, Stefano Leone, Carlo Meneghini, Nathan O'Callaghan, Antonella Sgura
Published 2014-01-01

G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells

by Roberta Amato, Martina Valenzuela, Francesco Berardinelli, Erica Salvati, Carmen Maresca, Stefano Leone, Antonio Antoccia, Antonella Sgura
Published 2020-03-01

Extracellular Neuroglobin as a Stress-Induced Factor Activating Pre-Adaptation Mechanisms against Oxidative Stress and Chemotherapy-Induced Cell Death in Breast Cancer

by Marco Fiocchetti, Virginia Solar Fernandez, Marco Segatto, Stefano Leone, Paolo Cercola, Annalisa Massari, Francesco Cavaliere, Maria Marino
Published 2020-08-01

Ouabain and Digoxin Activate the Proteasome and the Degradation of the ERα in Cells Modeling Primary and Metastatic Breast Cancer

by Claudia Busonero, Stefano Leone, Fabrizio Bianchi, Elena Maspero, Marco Fiocchetti, Orazio Palumbo, Manuela Cipolletti, Stefania Bartoloni, Filippo Acconcia
Published 2020-12-01

Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function.

by Marco Fiocchetti, Manuela Cipolletti, Stefano Leone, Antonella Naldini, Fabio Carraro, Daniela Giordano, Cinzia Verde, Paolo Ascenzi, Maria Marino
Published 2016-01-01

Lithium Improves Survival of PC12 Pheochromocytoma Cells in High-Density Cultures and after Exposure to Toxic Compounds

by Cinzia Fabrizi, Stefania De Vito, Francesca Somma, Elena Pompili, Angela Catizone, Stefano Leone, Paola Lenzi, Francesco Fornai, Lorenzo Fumagalli
Published 2014-01-01

Reward-Related Behavioral, Neurochemical and Electrophysiological Changes in a Rat Model of Autism Based on Prenatal Exposure to Valproic Acid

by Sara Schiavi, Daniela Iezzi, Antonia Manduca, Stefano Leone, Francesca Melancia, Carmen Carbone, Michele Petrella, Guido Mannaioni, Alessio Masi, Alessio Masi, Viviana Trezza
Published 2019-10-01

Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier

by Elena Pompili, Viviana Ciraci, Stefano Leone, Valerio De Franchis, Pietro Familiari, Roberto Matassa, Giuseppe Familiari, Ada Maria Tata, Lorenzo Fumagalli, Cinzia Fabrizi
Published 2020-03-01

Neuroprotective Effects of Curcumin in Methamphetamine-Induced Toxicity

by Larisa Ryskalin, Stefano Puglisi-Allegra, Gloria Lazzeri, Francesca Biagioni, Carla L. Busceti, Linda Balestrini, Andrea Fornasiero, Stefano Leone, Elena Pompili, Michela Ferrucci, Francesco Fornai
Published 2021-04-01

HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity.

by Giorgio Mangino, Marylinda Famiglietti, Caterina Capone, Caterina Veroni, Zulema Antonia Percario, Stefano Leone, Gianna Fiorucci, Sebastian Lülf, Giovanna Romeo, Cristina Agresti, Tiziana Persichini, Matthias Geyer, Elisabetta Affabris
Published 2015-01-01

Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells

by Jacopo Albanesi, Nelida Ines Noguera, Cristina Banella, Tommaso Colangelo, Elisabetta De Marinis, Stefano Leone, Orazio Palumbo, Maria Teresa Voso, Paolo Ascenzi, Clara Nervi, Fabrizio Bianchi, Alessandra di Masi
Published 2020-11-01

HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2.

by Giorgio Mangino, Zulema A Percario, Gianna Fiorucci, Gabriele Vaccari, Filippo Acconcia, Cristiano Chiarabelli, Stefano Leone, Alessia Noto, Florian A Horenkamp, Santiago Manrique, Giovanna Romeo, Fabio Polticelli, Matthias Geyer, Elisabetta Affabris
Published 2011-01-01

Protection by extra virgin olive oil against oxidative stress in vitro and in vivo. Chemical and biological studies on the health benefits due to a major component of the Mediterra...

by Miriam Rossi, Francesco Caruso, Lorraine Kwok, Grace Lee, Alessio Caruso, Fabio Gionfra, Elena Candelotti, Stuart L Belli, Nora Molasky, Kathleen M Raley-Susman, Stefano Leone, Tomáš Filipský, Daniela Tofani, Jens Pedersen, Sandra Incerpi
Published 2017-01-01

Protection of cells against oxidative stress by nanomolar levels of hydroxyflavones indicates a new type of intracellular antioxidant mechanism.

by Emanuele Lombardo, Cristian Sabellico, Jan Hájek, Veronika Staňková, Tomáš Filipský, Valentina Balducci, Paolo De Vito, Stefano Leone, Eugenia I Bavavea, Ilaria Proietti Silvestri, Giuliana Righi, Paolo Luly, Luciano Saso, Paolo Bovicelli, Jens Z Pedersen, Sandra Incerpi
Published 2013-01-01