Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome

by Luke Y.C. Chen, Catherine M. Biggs, Shahin Jamal, Sophie Stukas, Cheryl L. Wellington, Mypinder S. Sekhon
Published 2021-05-01

Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels

by Jerome Robert, Emily B Button, Brian Yuen, Megan Gilmour, Kevin Kang, Arvin Bahrabadi, Sophie Stukas, Wenchen Zhao, Iva Kulic, Cheryl L Wellington
Published 2017-10-01

LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice[S]

by Sophie Stukas, Lita Freeman, Michael Lee, Anna Wilkinson, Alice Ossoli, Boris Vaisman, Stephen Demosky, Jeniffer Chan, Veronica Hirsch-Reinshagen, Alan T. Remaley, Cheryl L. Wellington
Published 2014-08-01

An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia

by Jianjia Fan, Sophie Stukas, Charmaine Wong, Jennifer Chan, Sharon May, Nicole DeValle, Veronica Hirsch-Reinshagen, Anna Wilkinson, Michael N. Oda, Cheryl L. Wellington
Published 2011-09-01

ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1...

by Emily B. Button, Guilaine K. Boyce, Anna Wilkinson, Sophie Stukas, Arooj Hayat, Jianjia Fan, Brennan J. Wadsworth, Jerome Robert, Kris M. Martens, Cheryl L. Wellington
Published 2019-05-01

The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E.

by Dhananjay R Namjoshi, Georgina Martin, James Donkin, Anna Wilkinson, Sophie Stukas, Jianjia Fan, Michael Carr, Sepideh Tabarestani, Kelli Wuerth, Robert E W Hancock, Cheryl L Wellington
Published 2013-01-01

LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins

by Veronica Hirsch-Reinshagen, James Donkin, Sophie Stukas, Jennifer Chan, Anna Wilkinson, Jianjia Fan, John S. Parks, Jan Albert Kuivenhoven, Dieter Lu¨tjohann, Haydn Pritchard, Cheryl L. Wellington
Published 2009-05-01

ABCA1 influences neuroinflammation and neuronal death

by Joanna M. Karasinska, Willeke de Haan, Sonia Franciosi, Piers Ruddle, Jianjia Fan, Janine K. Kruit, Sophie Stukas, Dieter Lütjohann, David H. Gutmann, Cheryl L. Wellington, Michael R. Hayden
Published 2013-06-01

Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury

by Emily B. Button, Wai Hang Cheng, Carlos Barron, Honor Cheung, Asma Bashir, Jennifer Cooper, Jasmine Gill, Sophie Stukas, David C. Baron, Jerome Robert, Elyn M. Rowe, Peter A. Cripton, Cheryl L. Wellington
Published 2021-03-01

CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice

by Wai Hang Cheng, Kris M. Martens, Asma Bashir, Honor Cheung, Sophie Stukas, Ebrima Gibbs, Dhananjay R. Namjoshi, Emily B. Button, Anna Wilkinson, Carlos J. Barron, Neil R. Cashman, Peter A. Cripton, Cheryl L. Wellington
Published 2019-01-01

An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases

by Jerome Robert, Nicholas L. Weilinger, Li-Ping Cao, Stefano Cataldi, Emily B. Button, Sophie Stukas, Emma M. Martin, Philip Seibler, Megan Gilmour, Tara M. Caffrey, Elyn M. Rowe, Jianjia Fan, Brian MacVicar, Matthew J. Farrer, Cheryl L. Wellington
Published 2020-11-01

ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo

by Braydon L. Burgess, Pamela F. Parkinson, Margaret M. Racke, Veronica Hirsch-Reinshagen, Jianjia Fan, Charmaine Wong, Sophie Stukas, Louise Theroux, Jeniffer Y. Chan, James Donkin, Anna Wilkinson, Danielle Balik, Brian Christie, Judes Poirier, Dieter Lütjohann, Ronald B. DeMattos, Cheryl L. Wellington
Published 2008-06-01