Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

by Sayin, Volkan I, LeBoeuf, Sarah E, Singh, Simranjit X, Biancur, Douglas, Guzelhan, Betul S, Alvarez, Samantha W, Wu, Warren L, Karakousi, Triantafyllia R, Zavitsanou, Anastasia Maria, Ubriaco, Julian, Karagiannis, Dimitris, Morris, Patrick J, Thomas, Craig J, Possemato, Richard, Papagiannakopoulos, Thales, Davidson, Shawn M, Muir, Alexander, Vander Heiden, Matthew G.
Published 2018

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis

by Sayin, Volkan I., Singh, Simranjit X., LeBoeuf, Sarah E., Karakousi, Triantafyllia R., Martinez, Britney, Bronson, Roderick T., Prigge, Justin R., Schmidt, Edward E., Thomas, Craig J., Goparaju, Chandra, Davies, Angela, Dolgalev, Igor, Heguy, Adriana, Allaj, Viola, Poirier, John T., Moreira, Andre L., Rudin, Charles M., Pass, Harvey I., Papagiannakopoulos, Thales, Davidson, Shawn M., Bauer, Matthew R., Ellis, Donald Christian, Bhutkar, Arjun, Sanchez-Rivera, Francisco Javier, Subbaraj, Lakshmipriya, Vander Heiden, Matthew G., Jacks, Tyler E., Romero, Rodrigo,Ph. D.Massachusetts Institute of Technology
Published 2018