Detained introns are a novel, widespread class of post-transcriptionally spliced introns

by Sharp, Phillip A., Boutz, Paul, Bhutkar, Arjun
Published 2015

BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance

by Ferretti, Roberta, Bhutkar, Arjun, McNamara, Molly C., Lees, Jacqueline
Published 2017

Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development

by Dimitrova, Ivana Ljubomirova, Gocheva, Vasilena, Bhutkar, Arjun, Resnick, Rebecca, Jong, Robyn, Miller, Kathryn, Bendor, Jordan, Jacks, Tyler E.
Published 2018

Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

by Leung, Anthony, Bhutkar, Arjun (AJ), Chang, Paul, Vyas, Sejal Kamlesh, Rood, Jennifer Evelyn, Leung, Anthony, Sharp, Phillip A.
Published 2014

Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1-3 family

by JnBaptiste, Courtney Kenneil, Gurtan, Allan, Thai, Kevin K., Lu, Victoria, Bhutkar, Arjun, Jacks, Tyler E., Sharp, Phillip A.
Published 2017

Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs

by Leung, Anthony, Young, Amanda G., Bhutkar, Arjun (AJ), Zheng, Grace X., Bosson, Andrew David, Nielsen, Cydney B., Sharp, Phillip A.
Published 2012

CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer

by Ng, Sheng Rong, Rideout, William M., Akama-Garren, Elliot H., Bhutkar, Arjun, Mercer, Kim L., Schenkel, Jason M., Bronson, Roderick T., Jacks, Tyler E
Published 2020

Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop

by Oliver, Trudy, Meylan, Etienne, Chang, Gregory P., Xue, Wen, Burke, James R., Humpton, Timothy J., Hubbard, Diana D., Bhutkar, Arjun (AJ), Jacks, Tyler E.
Published 2015

Survival of pancreatic cancer cells lacking KRAS function

by Noll, Elisa M., Sprick, Martin R., Trumpp, Andreas, Muzumdar, Mandar, Chen, Pan-Yu, Dorans, Kimberly, Chung, Katherine Minjee, Bhutkar, Arjun, Hong, Erin, Jacks, Tyler E.
Published 2017

Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma

by Dayton, Talya L., Miller, Kathryn M., Bronson, Roderick T., Dayton, Talya L., Gocheva, Vasilena, Miller, Kathryn, Bhutkar, Arjun, Chidley, Caroline, Vander Heiden, Matthew G., Jacks, Tyler E.
Published 2018

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

by Papagiannakopoulos, Thales, Bauer, Matthew R., Davidson, Shawn M., Heimann, Megan Kristianne, Subbaraj, Lakshmipriya, Bhutkar, Arjun, Bartlebaugh, Jordan M. E., Vander Heiden, Matthew G., Jacks, Tyler E.
Published 2018

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

by Papagiannakopoulos, Thales, Romero, Rodrigo, Tammela, Tuomas, Bauer, Matthew R., Subbaraj, Lakshmipriya, Bronson, Roderick T., Xue, Wen, Sanchez-Rivera, Francisco Jav, Joshi, Nik, Bhutkar, Arjun, Jacks, Tyler E
Published 2015

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

by Jin, Chengcheng, Lagoudas, Georgia K, Bhutkar, Arjun, Ameh, Samuel, Sandel, Demi A, Liang, Xu Sue, Whary, Mark T., Blainey, Paul C, Fox, James G, Jacks, Tyler E
Published 2020

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts

by Gurtan, Allan M., Ravi, Arvind, Bosson, Andrew David, JnBaptiste, Courtney Kenneil, Bhutkar, Arjun (AJ), Whittaker, Charles A., Young, Richard A., Sharp, Phillip A., Rahl, Peter B.
Published 2014

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

by McFadden, David Glenn, Vernon, Amanda, Santiago, Philip M., Martinez-McFaline, Raul, Crowley, Denise M., McMahon, Martin, Sadow, Peter M., Bhutkar, Arjun, Jacks, Tyler E
Published 2014

Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma

by Clish, Clary B., Bronson, Roderick T., Dayton, Talya L., Gocheva, Vasilena, Miller, Kathryn, Israelsen, William James, Bhutkar, Arjun, Davidson, Shawn Michael, Luengo, Alba, Jacks, Tyler E., Vander Heiden, Matthew G.
Published 2017

Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1

by Ravi, Arvind, Gurtan, Allan M., Kumar, Madhu Sudhan, Chin, Christine, Lu, Victoria, Sharp, Phillip A., Bhutkar, Arjun (AJ), Lees, Jacqueline, Jacks, Tyler E., Sharp, Phillip A., Kumar, Madhu Sudhan
Published 2014

Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells

by Chen, Pan-Yu, Muzumdar, Mandar, Dorans, Kimberly, Robbins, Rebecca, Bhutkar, Arjun, Del Rosario, Amanda M, Mertins, Philipp, Qiao, Jana, Schafer, Anette Claudia, Gertler, Frank, Carr, Steven A, Jacks, Tyler E
Published 2020

Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis

by Li, Carman Man-Chung, Gocheva, Vasilena, Wang, Shi Yun, Date, Saya R., Ng, Sheng Rong, Whittaker, Charles A., Bronson, Roderick T., Snyder, Eric L., Oudin, Madeleine Julie, Gertler, Frank, Bhutkar, Arjun, Jacks, Tyler E
Published 2016