Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds

by Marta Perez-Rando, Simon Dujardin, Rachel E. Bennett, Caitlin Commins, Tara Nibhanupudy, Bradley T. Hyman
Published 2020-10-01

Tau reduction in aged mice does not impact Microangiopathy

by Rachel E. Bennett, Miwei Hu, Analiese Fernandes, Marta Perez-Rando, Ashley Robbins, Tarun Kamath, Simon Dujardin, Bradley T. Hyman
Published 2020-08-01

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

by Maria Calvo-Rodriguez, Steven S. Hou, Austin C. Snyder, Simon Dujardin, Hamid Shirani, K. Peter R. Nilsson, Brian J. Bacskai
Published 2019-11-01

What is the evidence that tau pathology spreads through prion-like propagation?

by Amrit Mudher, Morvane Colin, Simon Dujardin, Miguel Medina, Ilse Dewachter, Seyedeh Maryam Alavi Naini, Eva-Maria Mandelkow, Eckhard Mandelkow, Luc Buée, Michel Goedert, Jean-Pierre Brion
Published 2017-12-01

Ectosomes: a new mechanism for non-exosomal secretion of tau protein.

by Simon Dujardin, Séverine Bégard, Raphaëlle Caillierez, Cédrick Lachaud, Lucie Delattre, Sébastien Carrier, Anne Loyens, Marie-Christine Galas, Luc Bousset, Ronald Melki, Gwennaëlle Aurégan, Philippe Hantraye, Emmanuel Brouillet, Luc Buée, Morvane Colin
Published 2014-01-01

Different tau species lead to heterogeneous tau pathology propagation and misfolding

by Simon Dujardin, Séverine Bégard, Raphaëlle Caillierez, Cédrick Lachaud, Sébastien Carrier, Sarah Lieger, Jose A. Gonzalez, Vincent Deramecourt, Nicole Déglon, Claude-Alain Maurage, Matthew P. Frosch, Bradley T. Hyman, Morvane Colin, Luc Buée
Published 2018-11-01

Selection of an Efficient AAV Vector for Robust CNS Transgene Expression

by Killian S. Hanlon, Jonah C. Meltzer, Tetyana Buzhdygan, Ming J. Cheng, Miguel Sena-Esteves, Rachel E. Bennett, Timothy P. Sullivan, Roshanak Razmpour, Yi Gong, Carrie Ng, Josette Nammour, Daniela Maiz, Simon Dujardin, Servio H. Ramirez, Eloise Hudry, Casey A. Maguire
Published 2019-12-01