Two-dimensional electrophoresis of tau mutants reveals specific phosphorylation pattern likely linked to early tau conformational changes.

by Alexis Bretteville, Kunie Ando, Antoine Ghestem, Anne Loyens, Séverine Bégard, Jean-Claude Beauvillain, Nicolas Sergeant, Malika Hamdane, Luc Buée
Published 2009-01-01

Intracellular pH regulates amyloid precursor protein intracellular domain accumulation

by Valérie Vingtdeux, Malika Hamdane, Séverine Bégard, Anne Loyens, André Delacourte, Jean-Claude Beauvillain, Luc Buée, Philippe Marambaud, Nicolas Sergeant
Published 2007-03-01

Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism

by Valérie Vingtdeux, Malika Hamdane, Marie Gompel, Séverine Bégard, Hervé Drobecq, Antoine Ghestem, Marie-Eve Grosjean, Vesna Kostanjevecki, Pierre Grognet, Eugeen Vanmechelen, Luc Buée, André Delacourte, Nicolas Sergeant
Published 2005-11-01

Isolation of microglia-derived extracellular vesicles: towards miRNA signatures and neuroprotection

by Quentin Lemaire, Antonella Raffo-Romero, Tanina Arab, Christelle Van Camp, Francesco Drago, Stefano Forte, Jean-Pascal Gimeno, Séverine Begard, Morvane Colin, Jacopo Vizioli, Pierre-Eric Sautière, Michel Salzet, Christophe Lefebvre
Published 2019-12-01

AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation

by Claudia Marinangeli, Sébastien Didier, Tariq Ahmed, Raphaelle Caillerez, Manon Domise, Charlotte Laloux, Séverine Bégard, Sébastien Carrier, Morvane Colin, Philippe Marchetti, Bart Ghesquière, Detlef Balschun, Luc Buée, Jérôme Kluza, Valérie Vingtdeux
Published 2018-11-01

Ectosomes: a new mechanism for non-exosomal secretion of tau protein.

by Simon Dujardin, Séverine Bégard, Raphaëlle Caillierez, Cédrick Lachaud, Lucie Delattre, Sébastien Carrier, Anne Loyens, Marie-Christine Galas, Luc Bousset, Ronald Melki, Gwennaëlle Aurégan, Philippe Hantraye, Emmanuel Brouillet, Luc Buée, Morvane Colin
Published 2014-01-01

Different tau species lead to heterogeneous tau pathology propagation and misfolding

by Simon Dujardin, Séverine Bégard, Raphaëlle Caillierez, Cédrick Lachaud, Sébastien Carrier, Sarah Lieger, Jose A. Gonzalez, Vincent Deramecourt, Nicole Déglon, Claude-Alain Maurage, Matthew P. Frosch, Bradley T. Hyman, Morvane Colin, Luc Buée
Published 2018-11-01