Flavonoids from Engineered Tomatoes Inhibit Gut Barrier Pro-inflammatory Cytokines and Chemokines, via SAPK/JNK and p38 MAPK Pathways

by Matthew L. Tomlinson, Matthew L. Tomlinson, Eugenio Butelli, Cathie Martin, Simon R. Carding, Simon R. Carding
Published 2017-12-01

Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health

by Aimée Parker, Sonia Fonseca, Simon R. Carding
Published 2020-03-01

Drug-microbiota interactions and treatment response: Relevance to rheumatoid arthritis

by Ellie Sayers, Alex MacGregor, Simon R. Carding
Published 2018-10-01

Age-Associated Decline in Dendritic Cell Function and the Impact of Mediterranean Diet Intervention in Elderly Subjects

by Sarah J. Clements, Sarah J. Clements, Monica Maijo, Kamal Ivory, Claudio Nicoletti, Claudio Nicoletti, Simon R. Carding, Simon R. Carding
Published 2017-12-01

In Silico Analysis of the Small Molecule Content of Outer Membrane Vesicles Produced by Bacteroides thetaiotaomicron Indicates an Extensive Metabolic Link between Microbe and Host

by William A. Bryant, Régis Stentz, Gwenaelle Le Gall, Michael J. E. Sternberg, Simon R. Carding, Simon R. Carding, Thomas Wilhelm
Published 2017-12-01

Modelling the spatio-temporal cell dynamics reveals novel insights on cell differentiation and proliferation in the small intestinal crypt.

by Carmen Pin, Alastair J M Watson, Simon R Carding
Published 2012-01-01

A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)?

by Navena Navaneetharaja, Verity Griffiths, Tom Wileman, Simon R. Carding
Published 2016-06-01

Use of genetically modified bacteria for drug delivery in humans: Revisiting the safety aspect

by Udo Wegmann, Ana Lucia Carvalho, Martin Stocks, Simon R. Carding
Published 2017-05-01

Thymic Stromal-Cell Abnormalities and Dysregulated T-Cell Development in IL-2-Deficient Mice

by Tannishtha Reya, Hamid Bassiri, Renée Biancaniello, Simon R. Carding
Published 1998-01-01

Regulation of Enteroendocrine Cell Networks by the Major Human Gut Symbiont Bacteroides thetaiotaomicron

by Amisha Modasia, Aimee Parker, Emily Jones, Regis Stentz, Arlaine Brion, Andrew Goldson, Marianne Defernez, Tom Wileman, Tom Wileman, L. Ashley Blackshaw, Simon R. Carding, Simon R. Carding
Published 2020-11-01

The Uptake, Trafficking, and Biodistribution of Bacteroides thetaiotaomicron Generated Outer Membrane Vesicles

by Emily J. Jones, Catherine Booth, Sonia Fonseca, Aimee Parker, Kathryn Cross, Ariadna Miquel-Clopés, Isabelle Hautefort, Ulrike Mayer, Tom Wileman, Tom Wileman, Régis Stentz, Simon R. Carding, Simon R. Carding
Published 2020-02-01

The gut virome: the ‘missing link’ between gut bacteria and host immunity?

by Indrani Mukhopadhya, Jonathan P. Segal, Simon R. Carding, Ailsa L. Hart, Georgina L. Hold
Published 2019-03-01

Genome Characterization of a Novel Wastewater Bacteroides fragilis Bacteriophage (vB_BfrS_23) and its Host GB124

by Mohammad A. Tariq, Fiona Newberry, Fiona Newberry, Rik Haagmans, Rik Haagmans, Catherine Booth, Tom Wileman, Tom Wileman, Lesley Hoyles, Martha R. J. Clokie, James Ebdon, Simon R. Carding, Simon R. Carding
Published 2020-10-01

One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression...

by Monica Maijo, Kamal Ivory, Sarah J. Clements, Jack R. Dainty, Amy Jennings, Rachel Gillings, Susan Fairweather-Tait, Massimo Gulisano, Aurelia Santoro, Aurelia Santoro, Claudio Franceschi, Simon R. Carding, Simon R. Carding, Claudio Nicoletti, Claudio Nicoletti
Published 2018-07-01

Preterm Infants Harbour a Rapidly Changing Mycobiota That Includes <i>Candida</i> Pathobionts

by Stephen A. James, Sarah Phillips, Andrea Telatin, David Baker, Rebecca Ansorge, Paul Clarke, Lindsay J. Hall, Simon R. Carding
Published 2020-11-01

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

by Lesley Hoyles, Tom Snelling, Umm-Kulthum Umlai, Jeremy K. Nicholson, Simon R. Carding, Robert C. Glen, Simon McArthur
Published 2018-03-01

A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium.

by Oliver J Maclaren, Aimée Parker, Carmen Pin, Simon R Carding, Alastair J M Watson, Alexander G Fletcher, Helen M Byrne, Philip K Maini
Published 2017-07-01

Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge.

by Catherine R Walker, Isabelle Hautefort, Jane E Dalton, Karin Overweg, Charlotte E Egan, Roy J Bongaerts, Darren J Newton, Sheena M Cruickshank, Elizabeth M Andrew, Simon R Carding
Published 2013-01-01

A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut

by Régis Stentz, Samantha Osborne, Nikki Horn, Arthur W.H. Li, Isabelle Hautefort, Roy Bongaerts, Marine Rouyer, Paul Bailey, Stephen B. Shears, Andrew M. Hemmings, Charles A. Brearley, Simon R. Carding
Published 2014-02-01

Bioengineering commensal bacteria-derived outer membrane vesicles for delivery of biologics to the gastrointestinal and respiratory tract

by Ana L. Carvalho, Sonia Fonseca, Ariadna Miquel-Clopés, Kathryn Cross, Khoon-S. Kok, Udo Wegmann, Katherine Gil-Cardoso, Eleanor G. Bentley, Sanaria H.M. Al Katy, Janine L. Coombes, Anja Kipar, Regis Stentz, James P. Stewart, Simon R. Carding
Published 2019-12-01