Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.

by Chiung-Kuang Chen, Siegfried S F Leung, Christophe Guilbert, Matthew P Jacobson, James H McKerrow, Larissa M Podust
Published 2010-04-01

Chemical–biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

by Jonathan W. Choy, Clifford Bryant, Claudia M. Calvet, Patricia S. Doyle, Shamila S. Gunatilleke, Siegfried S. F. Leung, Kenny K. H. Ang, Steven Chen, Jiri Gut, Juan A. Oses-Prieto, Jonathan B. Johnston, Michelle R. Arkin, Alma L. Burlingame, Jack Taunton, Matthew P. Jacobson, James M. McKerrow, Larissa M. Podust, Adam R. Renslo
Published 2013-01-01