Tricellular Tight Junctions in the Inner Ear

by Shin-ichiro Kitajiri, Tatsuya Katsuno
Published 2016-01-01

Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.

by Tomohito Higashi, Tatsuya Katsuno, Shin-Ichiro Kitajiri, Mikio Furuse
Published 2015-01-01

Detailed Clinical Features of Deafness Caused by a Claudin-14 Variant

by Tomohiro Kitano, Shin-ichiro Kitajiri, Shin-ya Nishio, Shin-ichi Usami
Published 2019-09-01

Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells

by Shin-ichiro Kitajiri, Tatsuya Katsuno, Hiroyuki Sasaki, Juichi Ito, Mikio Furuse, Shoichiro Tsukita
Published 2014-07-01

Microarray analyses of otospheres derived from the cochlea in the inner ear identify putative transcription factors that regulate the characteristics of otospheres.

by Takehiro Iki, Michihiro Tanaka, Shin-Ichiro Kitajiri, Tomoko Kita, Yuri Kawasaki, Akifumi Mizukoshi, Wataru Fujibuchi, Takayuki Nakagawa, Tatsutoshi Nakahata, Juichi Ito, Koichi Omori, Megumu K Saito
Published 2017-01-01

A novel splice site mutation of myosin VI in mice leads to stereociliary fusion caused by disruption of actin networks in the apical region of inner ear hair cells.

by Yuta Seki, Yuki Miyasaka, Sari Suzuki, Kenta Wada, Shumpei P Yasuda, Kunie Matsuoka, Yasuhiro Ohshiba, Kentaro Endo, Rie Ishii, Hiroshi Shitara, Shin-Ichiro Kitajiri, Naomi Nakagata, Hirohide Takebayashi, Yoshiaki Kikkawa
Published 2017-01-01

Mid-Frequency Hearing Loss Is Characteristic Clinical Feature of <i>OTOA</i>-Associated Hearing Loss

by Kenjiro Sugiyama, Hideaki Moteki, Shin-ichiro Kitajiri, Tomohiro Kitano, Shin-ya Nishio, Tomomi Yamaguchi, Keiko Wakui, Satoko Abe, Akiko Ozaki, Remi Motegi, Hirooki Matsui, Masato Teraoka, Yumiko Kobayashi, Tomoki Kosho, Shin-ichi Usami
Published 2019-09-01

Downsloping high-frequency hearing loss due to inner ear tricellular tight junction disruption by a novel ILDR1 mutation in the Ig-like domain.

by Nayoung K D Kim, Tomohito Higashi, Kyoung Yeul Lee, Ah Reum Kim, Shin-ichiro Kitajiri, Min Young Kim, Mun Young Chang, Veronica Kim, Seung-Ha Oh, Dongsup Kim, Mikio Furuse, Woong-Yang Park, Byung Yoon Choi
Published 2015-01-01

Clinical Characteristics and In Vitro Analysis of <i>MYO6</i> Variants Causing Late-Onset Progressive Hearing Loss

by Shin-ichiro Oka, Timothy F. Day, Shin-ya Nishio, Hideaki Moteki, Maiko Miyagawa, Shinya Morita, Shuji Izumi, Tetsuo Ikezono, Satoko Abe, Jun Nakayama, Misako Hyogo, Nobuhiko Okamoto, Natsumi Uehara, Chie Oshikawa, Shin-ichiro Kitajiri, Shin-ichi Usami
Published 2020-03-01

Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome

by Mengnan Li, Shin-ya Nishio, Chie Naruse, Meghan Riddell, Sabrina Sapski, Tatsuya Katsuno, Takao Hikita, Fatemeh Mizapourshafiyi, Fiona M. Smith, Leanne T. Cooper, Min Goo Lee, Masahide Asano, Thomas Boettger, Marcus Krueger, Astrid Wietelmann, Johannes Graumann, Bryan W. Day, Andrew W. Boyd, Stefan Offermanns, Shin-ichiro Kitajiri, Shin-ichi Usami, Masanori Nakayama
Published 2020-03-01