A therapeutic chemical chaperone inhibits cholera intoxication and unfolding/translocation of the cholera toxin A1 subunit.

by Michael Taylor, Tuhina Banerjee, Fernando Navarro-Garcia, Jazmin Huerta, Shane Massey, Mansfield Burlingame, Abhay H Pande, Suren A Tatulian, Ken Teter
Published 2011-04-01

Mucosal Challenge Ferret Models of Ebola Virus Disease

by Trevor Brasel, Jason E. Comer, Shane Massey, Jeanon Smith, Jennifer Smith, Matthew Hyde, Andrew Kocsis, Melicia Gainey, Nancy Niemuth, Cheryl Triplett, Thomas Rudge
Published 2021-03-01

Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir

by Jason E. Comer, Olivier Escaffre, Natasha Neef, Trevor Brasel, Terry L. Juelich, Jennifer K. Smith, Jeanon Smith, Birte Kalveram, David D. Perez, Shane Massey, Lihong Zhang, Alexander N. Freiberg
Published 2019-02-01

STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV)

by Olivier Escaffre, Terry L. Juelich, Natasha Neef, Shane Massey, Jeanon Smith, Trevor Brasel, Jennifer K. Smith, Birte Kalveram, Lihong Zhang, David Perez, Tetsuro Ikegami, Alexander N. Freiberg, Jason E. Comer
Published 2021-07-01

Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease.

by Nancy A Niemuth, Dawn Fallacara, Cheryl A Triplett, Sanjay M Tamrakar, Alisha Rajbhandari, Clint Florence, Lucy Ward, Anthony Griffiths, Ricardo Carrion, Yenny Goez-Gazi, Kendra J Alfson, Hilary M Staples, Trevor Brasel, Jason E Comer, Shane Massey, Jeanon Smith, Andrew Kocsis, Jake Lowry, Sara C Johnston, Aysegul Nalca, Arthur J Goff, Amy C Shurtleff, Margaret L Pitt, John Trefry, Michael P Fay
Published 2021-01-01

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeut...

by Conrad E Z Chan, Shirley G K Seah, De Hoe Chye, Shane Massey, Maricela Torres, Angeline P C Lim, Steven K K Wong, Jacklyn J Y Neo, Pui San Wong, Jie Hui Lim, Gary S L Loh, Dongling Wang, Jerome D Boyd-Kirkup, Siyu Guan, Dipti Thakkar, Guo Hui Teo, Kiren Purushotorman, Paul E Hutchinson, Barnaby E Young, Jenny G Low, Paul A MacAry, Hannes Hentze, Venkateshan S Prativadibhayankara, Kantharaj Ethirajulu, Jason E Comer, Chien-Te K Tseng, Alan D T Barrett, Piers J Ingram, Trevor Brasel, Brendon John Hanson
Published 2021-01-01