Automation of Infectious Focus Assay for Determination of Filovirus Titers and Direct Comparison to Plaque and TCID₅₀ Assays

by Patrick T. Keiser, Manu Anantpadma, Hilary Staples, Ricardo Carrion, Robert A. Davey
Published 2021-01-01

Development of a Lethal Intranasal Exposure Model of Ebola Virus in the Cynomolgus Macaque

by Kendra J. Alfson, Laura E. Avena, Gabriella Worwa, Ricardo Carrion, Anthony Griffiths
Published 2017-10-01

Intramuscular Exposure of <i>Macaca fascicularis</i> to Low Doses of Low Passage- or Cell Culture-Adapted Sudan Virus or Ebola Virus

by Kendra J. Alfson, Laura E. Avena, Michael W. Beadles, Gabriella Worwa, Melanie Amen, Jean L. Patterson, Ricardo Carrion, Anthony Griffiths
Published 2018-11-01

A Single Amino Acid Change in the Marburg Virus Glycoprotein Arises during Serial Cell Culture Passages and Attenuates the Virus in a Macaque Model of Disease

by Kendra J. Alfson, Laura E. Avena, Jenny Delgado, Michael W. Beadles, Jean L. Patterson, Ricardo Carrion, Anthony Griffiths, W. Paul Duprex
Published 2018-01-01

Intradermal Immunization of EBOV VLPs in Guinea Pigs Induces Broader Antibody Responses Against GP Than Intramuscular Injection

by Ying Liu, Ying Liu, Zhiyuan Wen, Zhiyuan Wen, Ricardo Carrion, Jerritt Nunneley, Hilary Staples, Anysha Ticer, Jean L. Patterson, Richard W. Compans, Ling Ye, Chinglai Yang
Published 2020-02-01

Transcriptome analysis of human peripheral blood mononuclear cells exposed to Lassa virus and to the attenuated Mopeia/Lassa reassortant 29 (ML29), a vaccine candidate.

by Juan Carlos Zapata, Ricardo Carrion, Jean L Patterson, Oswald Crasta, Yan Zhang, Sachin Mani, Marti Jett, Bhawna Poonia, Mahmoud Djavani, David M White, Igor S Lukashevich, Maria S Salvato
Published 2013-01-01

Experimental cross-species infection of common marmosets by titi monkey adenovirus.

by Guixia Yu, Shigeo Yagi, Ricardo Carrion, Eunice C Chen, Maria Liu, Kathleen M Brasky, Robert E Lanford, Kristi R Kelly, Karen L Bales, David P Schnurr, Don R Canfield, Jean L Patterson, Charles Y Chiu
Published 2013-01-01

Development of a Well-Characterized Rhesus Macaque Model of Ebola Virus Disease for Support of Product Development

by Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Hilary Staples, Marc Mattix, Anysha Ticer, Benjamin Klaffke, Kaylee Stanfield, Priscilla Escareno, Patrick Keiser, Anthony Griffiths, Ying-Liang Chou, Nancy Niemuth, Gabe T. Meister, Chris M. Cirimotich, Ricardo Carrion
Published 2021-02-01

Potential Impact of a 2-Person Security Rule on BioSafety Level 4 Laboratory Workers

by James W. LeDuc, Kevin Anderson, Marshall E. Bloom, Ricardo Carrion, Heinz Feldmann, J. Patrick Fitch, Joan B. Geisbert, Thomas W. Geisbert, Michael R. Holbrook, Peter B. Jahrling, Thomas G. Ksiazek, Jean Patterson, Pierre E. Rollin
Published 2009-07-01

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

by Bruce A. Rosa, Mushtaq Ahmed, Dhiraj K. Singh, José Alberto Choreño-Parra, Journey Cole, Luis Armando Jiménez-Álvarez, Tatiana Sofía Rodríguez-Reyna, Bindu Singh, Olga Gonzalez, Ricardo Carrion, Larry S. Schlesinger, John Martin, Joaquín Zúñiga, Makedonka Mitreva, Deepak Kaushal, Shabaana A. Khader
Published 2021-03-01

Correction: A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus sp...

by Benoit Callendret, Jort Vellinga, Kerstin Wunderlich, Ariane Rodriguez, Robin Steigerwald, Ulrike Dirmeier, Cedric Cheminay, Ariane Volkmann, Trevor Brasel, Ricardo Carrion, Luis D Giavedoni, Jean L Patterson, Chad E Mire, Thomas W Geisbert, Jay W Hooper, Mo Weijtens, Jutta Hartkoorn-Pasma, Jerome Custers, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn
Published 2018-01-01

A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non...

by Benoit Callendret, Jort Vellinga, Kerstin Wunderlich, Ariane Rodriguez, Robin Steigerwald, Ulrike Dirmeier, Cedric Cheminay, Ariane Volkmann, Trevor Brasel, Ricardo Carrion, Luis D Giavedoni, Jean L Patterson, Chad E Mire, Thomas W Geisbert, Jay W Hooper, Mo Weijtens, Jutta Hartkoorn-Pasma, Jerome Custers, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn
Published 2018-01-01

A systematic screen of FDA-approved drugs for inhibitors of biological threat agents.

by Peter B Madrid, Sidharth Chopra, Ian D Manger, Lynne Gilfillan, Tiffany R Keepers, Amy C Shurtleff, Carol E Green, Lalitha V Iyer, Holli Hutcheson Dilks, Robert A Davey, Andrey A Kolokoltsov, Ricardo Carrion, Jean L Patterson, Sina Bavari, Rekha G Panchal, Travis K Warren, Jay B Wells, Walter H Moos, Raelyn L Burke, Mary J Tanga
Published 2013-01-01

Nonhuman primate to human immunobridging to infer the protective effect of an Ebola virus vaccine candidate

by Ramon Roozendaal, Jenny Hendriks, Thierry van Effelterre, Bart Spiessens, Liesbeth Dekking, Laura Solforosi, Dominika Czapska-Casey, Viki Bockstal, Jeroen Stoop, Daniel Splinter, Sarah Janssen, Ben van Baelen, Nadia Verbruggen, Jan Serroyen, Eline Dekeyster, Ariane Volkmann, Yvonne Wollmann, Ricardo Carrion, Luis D. Giavedoni, Cynthia Robinson, Maarten Leyssen, Macaya Douoguih, Kerstin Luhn, Maria Grazia Pau, Jerry Sadoff, An Vandebosch, Hanneke Schuitemaker, Roland Zahn, Benoit Callendret
Published 2020-12-01

Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease.

by Nancy A Niemuth, Dawn Fallacara, Cheryl A Triplett, Sanjay M Tamrakar, Alisha Rajbhandari, Clint Florence, Lucy Ward, Anthony Griffiths, Ricardo Carrion, Yenny Goez-Gazi, Kendra J Alfson, Hilary M Staples, Trevor Brasel, Jason E Comer, Shane Massey, Jeanon Smith, Andrew Kocsis, Jake Lowry, Sara C Johnston, Aysegul Nalca, Arthur J Goff, Amy C Shurtleff, Margaret L Pitt, John Trefry, Michael P Fay
Published 2021-01-01

Abnormally Large Baseline P300 Amplitude Is Associated With Conversion to Psychosis in Clinical High Risk Individuals With a History of Autism: A Pilot Study

by Jennifer H. Foss-Feig, Sylvia B. Guillory, Brian J. Roach, Eva Velthorst, Holly Hamilton, Holly Hamilton, Peter Bachman, Aysenil Belger, Ricardo Carrion, Erica Duncan, Jason Johannesen, Gregory A. Light, Margaret Niznikiewicz, Jean M. Addington, Kristin S. Cadenhead, Tyrone D. Cannon, Barbara Cornblatt, Thomas McGlashan, Diana Perkins, Larry J. Seidman, William S. Stone, Ming Tsuang, Elaine F. Walker, Scott Woods, Carrie E. Bearden, Daniel H. Mathalon, Daniel H. Mathalon
Published 2021-02-01

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

by Matthew J. Gorman, Nita Patel, Mimi Guebre-Xabier, Alex L. Zhu, Caroline Atyeo, Krista M. Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jr., Jing-Hui Tian, Dansu Yuan, Kathryn A. Bowman, Bin Zhou, Sonia Maciejewski, Marisa E. McGrath, James Logue, Matthew B. Frieman, David Montefiori, Colin Mann, Sharon Schendel, Fatima Amanat, Florian Krammer, Erica Ollmann Saphire, Douglas A. Lauffenburger, Ann M. Greene, Alyse D. Portnoff, Michael J. Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Galit Alter
Published 2021-09-01

Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice

by Fatai S. Oladunni, Jun-Gyu Park, Paula A. Pino, Olga Gonzalez, Anwari Akhter, Anna Allué-Guardia, Angélica Olmo-Fontánez, Shalini Gautam, Andreu Garcia-Vilanova, Chengjin Ye, Kevin Chiem, Colwyn Headley, Varun Dwivedi, Laura M. Parodi, Kendra J. Alfson, Hilary M. Staples, Alyssa Schami, Juan I. Garcia, Alison Whigham, Roy Neal Platt, Michal Gazi, Jesse Martinez, Colin Chuba, Stephanie Earley, Oscar H. Rodriguez, Stephanie Davis Mdaki, Katrina N. Kavelish, Renee Escalona, Cory R. A. Hallam, Corbett Christie, Jean L. Patterson, Tim J. C. Anderson, Ricardo Carrion, Edward J. Dick, Shannan Hall-Ursone, Larry S. Schlesinger, Xavier Alvarez, Deepak Kaushal, Luis D. Giavedoni, Joanne Turner, Luis Martinez-Sobrido, Jordi B. Torrelles
Published 2020-11-01