A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery

by Shalek, Alexander
Published 2022

Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage

by Shalek, Alexander
Published 2022

MERFISHing for spatial context

by Satija, Rahul, Shalek, Alexander K
Published 2018

Single-cell analyses to tailor treatments

by Benson, Mikael, Shalek, Alexander K
Published 2018

Scaling by shrinking: empowering single-cell 'omics' with microfluidic devices

by Weitz, David A., Prakadan, Sanjay, Shalek, Alexander K
Published 2018

The Human Cell Atlas & Equity: Lessons Learned

by Majumder, Partha P, Mhlanga, Musa M, Shalek, Alexander K
Published 2022

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

by Ordovas-Montanes, Jose Manuel, Graham, Daniel B., Shalek, Alexander K, Xavier, Ramnik Joseph, Regev, Aviv
Published 2020

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration

by Mohammadi, Shahin, Davila Velderrain, Jose, Goods, Brittany A., Shalek, Alexander K, Love, Christopher J., Kellis, Manolis
Published 2020

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput

by Bryson, Bryan D, Butler, Andrew, Satija, Rahul, Fortune, Sarah, Love, J Christopher, Gierahn, Todd Michael, Wadsworth, Marc Havens, Hughes, Travis K., Shalek, Alexander K
Published 2018

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies

by Martin-Gayo, Enrique, Gao, Ce, Chen, Hsiao Rong, Ouyang, Zhengyu, Kim, Dhohyung, Kolb, Kellie Elizabeth, Shalek, Alexander K, Walker, Bruce D., Lichterfeld, Mathias, Yu, Xu G.
Published 2020

Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses

by Douam, Florian, Hrebikova, Gabriela, Fant, Bruno, Leach, Robert, Parsons, Lance, Wang, Wei, Gaska, Jenna M., Winer, Benjamin Y., Heller, Brigitte, Ploss, Alexander, Ziegler, Carly, Shalek, Alexander K
Published 2019

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

by Avraham, Roi, Brown, Douglas, Penaranda, Cristina, Jijon, Humberto B, Trombetta, John J, Satija, Rahul, Xavier, Ramnik J, Hung, Deborah T, Haseley, Nathan Scott, Shalek, Alexander K, Regev, Aviv
Published 2016

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

by Li, Shuqiang, Darmanis, Spyros, Lundberg, Martin, Fredriksson, Simon, Landegren, Ulf, Gallant, Caroline J., Livak, Kenneth J., Genshaft, Alex S., Prakadan, Sanjay, Ziegler, Carly, Hong, Joyce, Regev, Aviv, Shalek, Alexander K
Published 2016

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

by Gaublomme, Jellert T, Yosef, Nir, Lee, Youjin, Gertner, Rona S, Yang, Li V, Wu, Chuan, Pandolfi, Pier Paolo, Mak, Tak, Satija, Rahul, Kuchroo, Vijay K, Park, Hongkun, Regev, Aviv, Shalek, Alexander K
Published 2016

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

by Martin-Gayo, Enrique, Ouyang, Zhengyu, Cronin, Jacqueline, Lichterfeld, Mathias, Yosef, Nir, Cole, Michael B., Walker, Bruce D., Yu, Xu G., Kolb, Kellie Elizabeth, Kazer, Samuel Weisgurt, Ordovas-Montanes, Jose Manuel, Shalek, Alexander K
Published 2018

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

by Martin-Gayo, Enrique, Cole, Michael B., Ouyang, Zhengyu, Cronin, Jacqueline, Lichterfeld, Mathias, Walker, Bruce D., Yosef, Nir, Yu, Xu G., Kolb, Kellie Elizabeth, Kazer, Samuel Weisgurt, Ordovas-Montanes, Jose Manuel, Shalek, Alexander K
Published 2018

Linking single-cell measurements of mass, growth rate, and gene expression

by Pelton, Kristine, De Smet, Frederik, Ligon, Keith L., Kimmerling, Robert John, Prakadan, Sanjay, Gupta, Alejandro J., Calistri, Nicholas L, Stevens, Mark M., Olcum, Selim A., Cermak, Nathan, Drake, Riley, Shalek, Alexander K, Manalis, Scott R
Published 2018

Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

by Ndhlovu, Zaza M., Kazer, Samuel Weisgurt, Nkosi, Thandeka, Ogunshola, Funsho, Muema, Daniel M., Anmole, Gursev, Swann, Shayda A., Moodley, Amber, Dong, Krista, Reddy, Tarylee, Brockman, Mark A., Shalek, Alexander K, Ndung'u, Thumbi, Walker, Bruce
Published 2020

A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood

by Sangesland, Maya, Yousif, Ashraf S., Ronsard, Larance, Kazer, Samuel Weisgurt, Zhu, Alex Lee, Gatter, G. James, Hayward, Matthew R., Barnes, Ralston M., Quirindongo-Crespo, Maricel, Rohrer, Daniel, Lonberg, Nils, Kwon, Douglas, Shalek, Alexander K, Lingwood, Daniel
Published 2020

Regulation of X-linked gene expression during early mouse development by

by Wang, Feng, Shin, JongDae, Shea, Jeremy M, Yu, Jun, Bošković, Ana, Byron, Meg, Zhu, Xiaochun, Lawrence, Jeanne B, Torres, Eduardo M, Zhu, Lihua J, Rando, Oliver J, Bach, Ingolf, Shalek, Alexander K, Regev, Aviv
Published 2017