Combinatorial prediction of marker panels from single‐cell transcriptomic data

by Regev, Aviv, Kuchroo, Vijay K, Singer, Meromit
Published 2020

A Model for How Signal Duration Can Determine Distinct Outcomes of Gene Transcription Programs

by Fowler, Kevin Daniel, Kuchroo, Vijay K., Chakraborty, Arup K.
Published 2012

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

by Wu, Chuan, Yosef, Nir, Thalhamer, Theresa, Zhu, Chen, Xiao, Sheng, Kishi, Yasuhiro, Regev, Aviv, Kuchroo, Vijay K.
Published 2013

RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression

by Meyer zu Horste, Gerd, Wu, Chuan, Wang, Chao, Cong, Le, Pawlak, Mathias, Lee, Youjin, Elyaman, Wassim, Xiao, Sheng, Regev, Aviv, Kuchroo, Vijay K
Published 2017

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

by Kishi, Yasuhiro, Kondo, Takaaki, Xiao, Sheng, Yosef, Nir, Gaublomme, Jellert, Wu, Chuan, Wang, Chao, Chihara, Norio, Regev, Aviv, Joller, Nicole, Kuchroo, Vijay K.
Published 2017

Oct1 and OCA-B are selectively required for CD4 memory T cell function

by Shakya, Arvind, Goren, Alon, Shalek, Alex, German, Cody N., Snook, Jeremy, Kuchroo, Vijay K., Yosef, Nir, Chan, Raymond C., Regev, Aviv, Williams, Matthew A., Tantin, Dean
Published 2018

Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation

by Karwacz, Katarzyna, Miraldi, Emily R, Pokrovskii, Maria, Madi, Asaf, Yosef, Nir, Wortman, Ivo, Chen, Xi, Watters, Aaron, Carriero, Nicholas, Awasthi, Amit, Bonneau, Richard, Littman, Dan, Kuchroo, Vijay K, Regev, Aviv
Published 2018

Induction and molecular signature of pathogenic T[subscript H]17 cells

by Lee, Youjin, Awasthi, Amit, Yosef, Nir, Quintana, Francisco J., Xiao, Sheng, Peters, Anneli, Wu, Chuan, Kleinewietfeld, Markus, Kunder, Sharon, Hafler, David A., Sobel, Raymond A., Regev, Aviv, Kuchroo, Vijay K.
Published 2014

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

by Gaublomme, Jellert T, Yosef, Nir, Lee, Youjin, Gertner, Rona S, Yang, Li V, Wu, Chuan, Pandolfi, Pier Paolo, Mak, Tak, Satija, Rahul, Kuchroo, Vijay K, Park, Hongkun, Regev, Aviv, Shalek, Alexander K
Published 2016

T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

by Sungnak, Waradon, Wagner, Allon, Kowalczyk, Monika S, Bod, Lloyd, Kye, Yoon-Chul, Sage, Peter T, Sharpe, Arlene H, Sobel, Raymond A, Quintana, Francisco J, Rozenblatt-Rosen, Orit, Regev, Aviv, Wang, Chao, Yosef, Nir, Kuchroo, Vijay K
Published 2021

Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses

by Wallrapp, Antonia, Burkett, Patrick R., Riesenfeld, Samantha J., Kim, Se-Jin, Christian, Elena, Abdulnour, Raja-Elie E., Thakore, Pratiksha I., Schnell, Alexandra, Lambden, Conner, Herbst, Rebecca H., Khan, Pavana, Tsujikawa, Kazutake, Xavier, Ramnik J., Chiu, Isaac M., Levy, Bruce D., Regev, Aviv, Kuchroo, Vijay K.
Published 2020

A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells

by Singer, Meromit, Cong, Le, Kowalczyk, Monika S., Zhang, Huiyuan, Nyman, Jackson, Sakuishi, Kaori, Kurtulus, Sema, Gennert, David, Xia, Junrong, Kwon, John Y.H, Nevin, James, Herbst, Rebecca H., Yanai, Itai, Rozenblatt-Rosen, Orit, Kuchroo, Vijay K., Anderson, Ana C., Marjanovic, Nemanja, Regev, Aviv, Wang, Chao
Published 2018

Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses

by Xu, Heping, Ding, Jiarui, Porter, Caroline, Wallrapp, Antonia, Tabaka, Marcin, Ma, Sai, Fu, Shujie, Guo, Xuanxuan, Riesenfeld, Samantha J., Su, Chienwen, Dionne, Danielle, Nguyen, Lan T., Lefkovith, Ariel, Ashenberg, Orr, Burkett, Patrick R., Shi, Hai Ning, Rozenblatt-Rosen, Orit, Graham, Daniel B., Kuchroo, Vijay K., Regev, Aviv, Xavier, Ramnik J.
Published 2020

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

by Wang, Chao, Yosef, Nir, Gaublomme, Jellert, Wu, Chuan, Lee, Youjin, Clish, Clary B, Kaminski, Jim, Xiao, Sheng, Zu Horste, Gerd Meyer, Pawlak, Mathias, Kishi, Yasuhiro, Joller, Nicole, Karwacz, Katarzyna, Zhu, Chen, Ordovas-Montanes, Maria, Madi, Asaf, Wortman, Ivo, Miyazaki, Toru, Sobel, Raymond A, Park, Hongkun, Regev, Aviv, Kuchroo, Vijay K
Published 2016

Dynamic regulatory network controlling TH17 cell differentiation

by Yosef, Nir, Shalek, Alex K., Gaublomme, Jellert T., Jin, Hulin, Lee, Youjin, Awasthi, Amit, Wu, Chuan, Karwacz, Katarzyna, Xiao, Sheng, Jorgolli, Marsela, Gennert, David, Satija, Rahul, Shakya, Arvind, Trombetta, John J., Pillai, Meenu R., Ratcliffe, Peter J., Coleman, Mathew L., Bix, Mark, Tantin, Dean, Park, Hongkun, Kuchroo, Vijay K., Regev, Aviv, Lu, Diana
Published 2013

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

by Huang, Yu-Hwa, Zhu, Chen, Kondo, Yasuyuki, Anderson, Ana C., Gandhi, Amit, Russell, Andrew, Dougan, Stephanie K., Petersen, Britt-Sabina, Melum, Espen, Pertel, Thomas, Clayton, Kiera L., Raab, Monika, Chen, Qiang, Beauchemin, Nicole, Yazaki, Paul J., Pyzik, Michal, Ostrowski, Mario A., Glickman, Jonathan N., Rudd, Christopher E., Franke, Andre, Petsko, Gregory A., Kuchroo, Vijay K., Blumberg, Richard S., Ploegh, Hidde
Published 2015

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation

by Wallrapp, Antonia, Riesenfeld, Samantha J., Burkett, Patrick R., Abdulnour, Raja-Elie E., Nyman, Jackson, Dionne, Danielle, Hofree, Matan, Cuoco, Michael S., Rodman, Christopher, Farouq, Daneyal, Haas, Brian J., Tickle, Timothy L., Trombetta, John J., Baral, Pankaj, Klose, Christoph S. N., Mahlakõiv, Tanel, Artis, David, Rozenblatt-Rosen, Orit, Chiu, Isaac M., Levy, Bruce D., Kowalczyk, Monika S., Regev, Aviv, Kuchroo, Vijay K.
Published 2018

Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms

by Xiao, Sheng, Yosef, Nir, Yang, Jianfei, Wang, Yonghui, Zhou, Ling, Zhu, Chen, Wu, Chuan, Baloglu, Erkan, Schmidt, Darby, Ramesh, Radha, Lobera, Mercedes, Sundrud, Mark S, Tsai, Pei-Yun, Xiang, Zhijun, Wang, Jinsong, Xu, Yan, Lin, Xichen, Kretschmer, Karsten, Rahl, Peter B, Zhong, Zhong, Hafler, David A, Ghosh, Shomir, Marson, Alexander, Kuchroo, Vijay K, Regev, Aviv, Young, Richard A.
Published 2017