A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.

by Nicholas C Wu, Seth J Zost, Andrew J Thompson, David Oyen, Corwin M Nycholat, Ryan McBride, James C Paulson, Scott E Hensley, Ian A Wilson
Published 2017-10-01

Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit

by Meghan O. Altman, Matthew Angel, Ivan Košík, Nídia S. Trovão, Seth J. Zost, James S. Gibbs, Lorenzo Casalino, Rommie E. Amaro, Scott E. Hensley, Martha I. Nelson, Jonathan W. Yewdell
Published 2019-04-01

Mapping person-to-person variation in viral mutations that escape polyclonal serum targeting influenza hemagglutinin

by Juhye M Lee, Rachel Eguia, Seth J Zost, Saket Choudhary, Patrick C Wilson, Trevor Bedford, Terry Stevens-Ayers, Michael Boeckh, Aeron C Hurt, Seema S Lakdawala, Scott E Hensley, Jesse D Bloom
Published 2019-08-01

Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans

by Seth J. Zost, Juhye Lee, Megan E. Gumina, Kaela Parkhouse, Carole Henry, Nicholas C. Wu, Chang-Chun D. Lee, Ian A. Wilson, Patrick C. Wilson, Jesse D. Bloom, Scott E. Hensley
Published 2019-12-01

The Crossroads of Glycoscience, Infection, and Immunology

by Tanya R. McKitrick, Margaret E. Ackerman, Robert M. Anthony, Clay S. Bennett, Michael Demetriou, Gregory A. Hudalla, Katharina Ribbeck, Stefan Ruhl, Christina M. Woo, Loretta Yang, Seth J. Zost, Ronald L. Schnaar, Tamara L. Doering
Published 2021-09-01

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies

by Norbert Pardi, Kaela Parkhouse, Ericka Kirkpatrick, Meagan McMahon, Seth J. Zost, Barbara L. Mui, Ying K. Tam, Katalin Karikó, Christopher J. Barbosa, Thomas D. Madden, Michael J. Hope, Florian Krammer, Scott E. Hensley, Drew Weissman
Published 2018-08-01

Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals

by Elaine C. Chen, Pavlo Gilchuk, Seth J. Zost, Naveenchandra Suryadevara, Emma S. Winkler, Carly R. Cabel, Elad Binshtein, Rita E. Chen, Rachel E. Sutton, Jessica Rodriguez, Samuel Day, Luke Myers, Andrew Trivette, Jazmean K. Williams, Edgar Davidson, Shuaizhi Li, Benjamin J. Doranz, Samuel K. Campos, Robert H. Carnahan, Curtis A. Thorne, Michael S. Diamond, James E. Crowe, Jr.
Published 2021-08-01

Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition

by Kevin J. Kramer, Nicole V. Johnson, Andrea R. Shiakolas, Naveenchandra Suryadevara, Sivakumar Periasamy, Nagarajan Raju, Jazmean K. Williams, Daniel Wrapp, Seth J. Zost, Lauren M. Walker, Steven C. Wall, Clinton M. Holt, Ching-Lin Hsieh, Rachel E. Sutton, Ariana Paulo, Rachel S. Nargi, Edgar Davidson, Benjamin J. Doranz, James E. Crowe, Jr., Alexander Bukreyev, Robert H. Carnahan, Jason S. McLellan, Ivelin S. Georgiev
Published 2021-10-01