AGE-induced neuronal cell death is enhanced in G2019S LRRK2 mutation with increased RAGE expression

by Hyun Jin Cho, Chengsong Xie, Huaibin Cai
Published 2018-01-01

Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice.

by Xi Chen, Chengsong Xie, Lixin Sun, Jinhui Ding, Huaibin Cai
Published 2015-01-01

Animal Models of Parkinson's Disease

by Yuzuru Imai, Katerina Venderova, David S. Park, Huaibin Cai, Enrico Schmidt
Published 2011-01-01

Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease

by Jie Dong, Sarah Hawes, Junbing Wu, Weidong Le, Weidong Le, Huaibin Cai
Published 2021-03-01

Optogenetic measurement of presynaptic calcium transients using conditional genetically encoded calcium indicator expression in dopaminergic neurons.

by Carmelo Sgobio, David A Kupferschmidt, Guohong Cui, Lixin Sun, Zheng Li, Huaibin Cai, David M Lovinger
Published 2014-01-01

Fingerprint analysis of Huolingshengji Formula and its neuroprotective effects in SOD1G93A mouse model of amyotrophic lateral sclerosis

by Qinming Zhou, Youjie Wang, Jingjing Zhang, Yaping Shao, Song Li, Yuan Wang, Huaibin Cai, Yi Feng, Weidong Le
Published 2018-01-01

Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer’s disease model mice and macaques

by Feng-Qin Zhou, Juan Jiang, Chelsea M. Griffith, Peter R. Patrylo, Huaibin Cai, Yaping Chu, Xiao-Xin Yan
Published 2018-04-01

Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice

by Jia Yu, Chen Lai, Hoon Shim, Chengsong Xie, Lixin Sun, Cai-Xia Long, Jinhui Ding, Yan Li, Huaibin Cai
Published 2018-03-01

Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

by Panpan Wang, Xi Chen, Yuanyuan Wang, Congcong Jia, Xinyao Liu, Ying Wang, Haifeng Wu, Huaibin Cai, Han-Ming Shen, Weidong Le
Published 2021-01-01

Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum

by Carmelo Sgobio, Junbing Wu, Wang Zheng, Xi Chen, Jing Pan, Armando G. Salinas, Margaret I. Davis, David M. Lovinger, Huaibin Cai
Published 2017-07-01

Function and Regulation of ALDH1A1-Positive Nigrostriatal Dopaminergic Neurons in Motor Control and Parkinson’s Disease

by Kathleen Carmichael, Kathleen Carmichael, Rebekah C. Evans, Rebekah C. Evans, Elena Lopez, Lixin Sun, Mantosh Kumar, Jinhui Ding, Zayd M. Khaliq, Huaibin Cai
Published 2021-05-01

Correction to: Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

by Xi Chen, Chengsong Xie, Wotu Tian, Lixin Sun, Wang Zheng, Sarah Hawes, Lisa Chang, Justin Kung, Jinhui Ding, Shengdi Chen, Weidong Le, Huaibin Cai
Published 2020-03-01

Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

by Xi Chen, Chengsong Xie, Wotu Tian, Lixin Sun, Zheng Wang, Sarah Hawes, Lisa Chang, Justin Kung, Jinhui Ding, Shengdi Chen, Weidong Le, Huaibin Cai
Published 2020-02-01

α-Synuclein Negatively Regulates Nurr1 Expression Through NF-κB-Related Mechanism

by Congcong Jia, Congcong Jia, Hongqian Qi, Hongqian Qi, Cheng Cheng, Cheng Cheng, Xuefei Wu, Zhaofei Yang, Zhaofei Yang, Huaibin Cai, Sheng Chen, Weidong Le, Weidong Le
Published 2020-05-01

Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.

by Xiao-Xin Yan, Yan Cai, Jarod Shelton, Si-Hao Deng, Xue-Gang Luo, Salvatore Oddo, Frank M Laferla, Huaibin Cai, Gregory M Rose, Peter R Patrylo
Published 2012-01-01

Leucine-Rich Repeat Kinase 2 (Lrrk2) Deficiency Diminishes the Development of Experimental Autoimmune Uveitis (EAU) and the Adaptive Immune Response.

by Wambui S Wandu, Cuiyan Tan, Osato Ogbeifun, Barbara P Vistica, Guangpu Shi, Samuel J H Hinshaw, Chengsong Xie, Xi Chen, Dennis M Klinman, Huaibin Cai, Igal Gery
Published 2015-01-01

The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling.

by Nicolas Dzamko, Francisco Inesta-Vaquera, Jiazhen Zhang, Chengsong Xie, Huaibin Cai, Simon Arthur, Li Tan, Hwanguen Choi, Nathanael Gray, Philip Cohen, Patrick Pedrioli, Kristopher Clark, Dario R Alessi
Published 2012-01-01

Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer’s Disease Mice and Wild-Type Littermates

by Feng Zhang, Feng Zhang, Rujia Zhong, Rujia Zhong, Song Li, Song Li, Zhenfa Fu, Zhenfa Fu, Cheng Cheng, Cheng Cheng, Huaibin Cai, Weidong Le, Weidong Le, Weidong Le
Published 2017-08-01

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function

by Jayanth S. Chandran, Xian Lin, Agustin Zapata, Ahmet Höke, Mika Shimoji, Shonagh O'Leary Moore, Matthew P. Galloway, Fiona M. Laird, Philip C. Wong, Donald L. Price, Kathleen R. Bailey, Jacqueline N. Crawley, Toni Shippenberg, Huaibin Cai
Published 2008-03-01

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum

by Xia Hu, Zhao-Lan Hu, Zheng Li, Chun-Sheng Ruan, Wen-Ying Qiu, Aihua Pan, Chang-Qi Li, Yan Cai, Lu Shen, Lu Shen, Yaping Chu, Bei-Sha Tang, Bei-Sha Tang, Huaibin Cai, Xin-Fu Zhou, Chao Ma, Xiao-Xin Yan, Xiao-Xin Yan
Published 2017-06-01