Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function

by Jiang, Tingting, Sánchez-Rivera, Francisco J, Soto-Feliciano, Yadira M, Yang, Qiyuan, Song, Chun-Qing, Bhuatkar, Arjun, Haynes, Cole M, Hemann, Michael T, Xue, Wen
Published 2022

Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1

by Romero, Rodrigo, Sánchez-Rivera, Francisco J, Westcott, Peter MK, Mercer, Kim L, Bhutkar, Arjun, Muir, Alexander, González Robles, Tania J, Lamboy Rodríguez, Swanny, Liao, Laura Z, Ng, Sheng Rong, Li, Leanne, Colón, Caterina I, Naranjo, Santiago, Beytagh, Mary Clare, Lewis, Caroline A, Hsu, Peggy P, Bronson, Roderick T, Vander Heiden, Matthew G, Jacks, Tyler
Published 2021

Stage-specific sensitivity to p53 restoration during lung cancer progression

by Feldser, David M., Kostova, Kamena K., Winslow, Monte Meier, Taylor, Sarah E., Cashman, Chris, Whittaker, Charles A., Resnick, Rebecca, Bronson, Roderick T., Hemann, Michael, Sanchez-Rivera, Francisco Jav, Jacks, Tyler E
Published 2012