A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

by Sébastien Thériault, Nathalie Gaudreault, Maxime Lamontagne, Mickael Rosa, Marie-Chloé Boulanger, David Messika-Zeitoun, Marie-Annick Clavel, Romain Capoulade, François Dagenais, Philippe Pibarot, Patrick Mathieu, Yohan Bossé
Published 2018-03-01

Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis

by Arnaud Chignon, Mickael Rosa, Marie-Chloé Boulanger, Déborah Argaud, Romain Devillers, Valentin Bon-Baret, Ghada Mkannez, Zhonglin Li, Anne Rufiange, Nathalie Gaudreault, David Gosselin, Sébastien Thériault, Yohan Bossé, Patrick Mathieu
Published 2021-03-01

Lipoprotein Proteomics and Aortic Valve Transcriptomics Identify Biological Pathways Linking Lipoprotein(a) Levels to Aortic Stenosis

by Raphaëlle Bourgeois, Jérôme Bourgault, Audrey-Anne Despres, Nicolas Perrot, Jakie Guertin, Arnaud Girard, Patricia L. Mitchell, Clarisse Gotti, Sylvie Bourassa, Corey A. Scipione, Nathalie Gaudreault, Michael B. Boffa, Marlys L. Koschinsky, Philippe Pibarot, Arnaud Droit, Sébastien Thériault, Patrick Mathieu, Yohan Bossé, Benoit J. Arsenault
Published 2021-07-01

Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

by Kim Valette, Zhonglin Li, Valentin Bon-Baret, Arnaud Chignon, Jean-Christophe Bérubé, Aida Eslami, Jennifer Lamothe, Nathalie Gaudreault, Philippe Joubert, Ma’en Obeidat, Maarten van den Berge, Wim Timens, Don D. Sin, David C. Nickle, Ke Hao, Catherine Labbé, Krystelle Godbout, Andréanne Côté, Michel Laviolette, Louis-Philippe Boulet, Patrick Mathieu, Sébastien Thériault, Yohan Bossé
Published 2021-06-01

Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography

by Audrey-Anne Després, BSc, Nicolas Perrot, MSc, Anthony Poulin, MD, Lionel Tastet, MSc, Mylène Shen, MSc, Hao Yu Chen, MSc, Raphaëlle Bourgeois, MSc, Mikaël Trottier, MD, Michel Tessier, MD, Jean Guimond, MD, Maxime Nadeau, TIM, James C. Engert, PhD, Sébastien Thériault, MD, MSc, Yohan Bossé, PhD, Joseph L. Witztum, MD, Patrick Couture, MD, Patrick Mathieu, MD, MSc, Marc R. Dweck, MD, Sotirios Tsimikas, MD, George Thanassoulis, MD, Philippe Pibarot, PhD, DVM, Marie-Annick Clavel, PhD, DVM, Benoit J. Arsenault, PhD
Published 2019-05-01

A Comparative Analysis of the Lipoprotein(a) and Low-Density Lipoprotein Proteomic Profiles Combining Mass Spectrometry and Mendelian Randomization

by Raphaëlle Bourgeois, MSc, Arnaud Girard, BSc, Nicolas Perrot, MSc, Jakie Guertin, BSc, Patricia L. Mitchell, PhD, Christian Couture, MSc, Clarisse Gotti, MSc, Sylvie Bourassa, PhD, Paolo Poggio, PhD, Elvira Mass, PhD, Romain Capoulade, PhD, Corey A. Scipione, PhD, Audrey-Anne Després, MSc, Patrick Couture, MD, PhD, Arnaud Droit, PhD, Philippe Pibarot, DVM, PhD, Michael B. Boffa, PhD, Sébastien Thériault, MD, MSc, Marlys L. Koschinsky, PhD, Patrick Mathieu, MD, MSc, Benoit J. Arsenault, PhD
Published 2021-04-01

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

by Ioanna Ntalla, Lu-Chen Weng, James H. Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Nathan R. Tucker, Seung Hoan Choi, Mark D. Chaffin, Carolina Roselli, Michael R. Barnes, Borbala Mifsud, Helen R. Warren, Caroline Hayward, Jonathan Marten, James J. Cranley, Maria Pina Concas, Paolo Gasparini, Thibaud Boutin, Ivana Kolcic, Ozren Polasek, Igor Rudan, Nathalia M. Araujo, Maria Fernanda Lima-Costa, Antonio Luiz P. Ribeiro, Renan P. Souza, Eduardo Tarazona-Santos, Vilmantas Giedraitis, Erik Ingelsson, Anubha Mahajan, Andrew P. Morris, Fabiola Del Greco M, Luisa Foco, Martin Gögele, Andrew A. Hicks, James P. Cook, Lars Lind, Cecilia M. Lindgren, Johan Sundström, Christopher P. Nelson, Muhammad B. Riaz, Nilesh J. Samani, Gianfranco Sinagra, Sheila Ulivi, Mika Kähönen, Pashupati P. Mishra, Nina Mononen, Kjell Nikus, Mark J. Caulfield, Anna Dominiczak, Sandosh Padmanabhan, May E. Montasser, Jeff R. O’Connell, Kathleen Ryan, Alan R. Shuldiner, Stefanie Aeschbacher, David Conen, Lorenz Risch, Sébastien Thériault, Nina Hutri-Kähönen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Olli T. Raitakari, Catriona L. K. Barnes, Harry Campbell, Peter K. Joshi, James F. Wilson, Aaron Isaacs, Jan A. Kors, Cornelia M. van Duijn, Paul L. Huang, Vilmundur Gudnason, Tamara B. Harris, Lenore J. Launer, Albert V. Smith, Erwin P. Bottinger, Ruth J. F. Loos, Girish N. Nadkarni, Michael H. Preuss, Adolfo Correa, Hao Mei, James Wilson, Thomas Meitinger, Martina Müller-Nurasyid, Annette Peters, Melanie Waldenberger, Massimo Mangino, Timothy D. Spector, Michiel Rienstra, Yordi J. van de Vegte, Pim van der Harst, Niek Verweij, Stefan Kääb, Katharina Schramm, Moritz F. Sinner, Konstantin Strauch, Michael J. Cutler, Diane Fatkin, Barry London, Morten Olesen, Dan M. Roden, M. Benjamin Shoemaker, J. Gustav Smith, Mary L. Biggs, Joshua C. Bis, Jennifer A. Brody, Bruce M. Psaty, Kenneth Rice, Nona Sotoodehnia, Alessandro De Grandi, Christian Fuchsberger, Cristian Pattaro, Peter P. Pramstaller, Ian Ford, J. Wouter Jukema, Peter W. Macfarlane, Stella Trompet, Marcus Dörr, Stephan B. Felix, Uwe Völker, Stefan Weiss, Aki S. Havulinna, Antti Jula, Katri Sääksjärvi, Veikko Salomaa, Xiuqing Guo, Susan R. Heckbert, Henry J. Lin, Jerome I. Rotter, Kent D. Taylor, Jie Yao, Renée de Mutsert, Arie C. Maan, Dennis O. Mook-Kanamori, Raymond Noordam, Francesco Cucca, Jun Ding, Edward G. Lakatta, Yong Qian, Kirill V. Tarasov, Daniel Levy, Honghuang Lin, Christopher H. Newton-Cheh, Kathryn L. Lunetta, Alison D. Murray, David J. Porteous, Blair H. Smith, Bruno H. Stricker, André Uitterlinden, Marten E. van den Berg, Jeffrey Haessler, Rebecca D. Jackson, Charles Kooperberg, Ulrike Peters, Alexander P. Reiner, Eric A. Whitsel, Alvaro Alonso, Dan E. Arking, Eric Boerwinkle, Georg B. Ehret, Elsayed Z. Soliman, Christy L. Avery, Stephanie M. Gogarten, Kathleen F. Kerr, Cathy C. Laurie, Amanda A. Seyerle, Adrienne Stilp, Solmaz Assa, M. Abdullah Said, M. Yldau van der Ende, Pier D. Lambiase, Michele Orini, Julia Ramirez, Stefan Van Duijvenboden, David O. Arnar, Daniel F. Gudbjartsson, Hilma Holm, Patrick Sulem, Gudmar Thorleifsson, Rosa B. Thorolfsdottir, Unnur Thorsteinsdottir, Emelia J. Benjamin, Andrew Tinker, Kari Stefansson, Patrick T. Ellinor, Yalda Jamshidi, Steven A. Lubitz, Patricia B. Munroe
Published 2020-05-01